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Antigen Production in Plant to Tackle Infectious Diseases Flare Up: The Case of SARS

Overview of attention for article published in Frontiers in Plant Science, February 2016
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (99th percentile)

Mentioned by

news
2 news outlets
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7 X users
googleplus
1 Google+ user

Readers on

mendeley
72 Mendeley
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Title
Antigen Production in Plant to Tackle Infectious Diseases Flare Up: The Case of SARS
Published in
Frontiers in Plant Science, February 2016
DOI 10.3389/fpls.2016.00054
Pubmed ID
Authors

Olivia C. Demurtas, Silvia Massa, Elena Illiano, Domenico De Martinis, Paul K. S. Chan, Paola Di Bonito, Rosella Franconi

Abstract

Severe acute respiratory syndrome (SARS) is a dangerous infection with pandemic potential. It emerged in 2002 and its aetiological agent, the SARS Coronavirus (SARS-CoV), crossed the species barrier to infect humans, showing high morbidity and mortality rates. No vaccines are currently licensed for SARS-CoV and important efforts have been performed during the first outbreak to develop diagnostic tools. Here we demonstrate the transient expression in Nicotiana benthamiana of two important antigenic determinants of the SARS-CoV, the nucleocapsid protein (N) and the membrane protein (M) using a virus-derived vector or agro-infiltration, respectively. For the M protein, this is the first description of production in plants, while for plant-derived N protein we demonstrate that it is recognized by sera of patients from the SARS outbreak in Hong Kong in 2003. The availability of recombinant N and M proteins from plants opens the way to further evaluation of their potential utility for the development of diagnostic and protection/therapy tools to be quickly manufactured, at low cost and with minimal risk, to face potential new highly infectious SARS-CoV outbreaks.

X Demographics

X Demographics

The data shown below were collected from the profiles of 7 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 72 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 1 1%
South Africa 1 1%
Unknown 70 97%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 15%
Student > Master 11 15%
Student > Ph. D. Student 8 11%
Student > Bachelor 7 10%
Other 3 4%
Other 14 19%
Unknown 18 25%
Readers by discipline Count As %
Agricultural and Biological Sciences 16 22%
Biochemistry, Genetics and Molecular Biology 13 18%
Medicine and Dentistry 3 4%
Unspecified 3 4%
Computer Science 2 3%
Other 15 21%
Unknown 20 28%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 20. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 January 2022.
All research outputs
#1,793,177
of 25,257,066 outputs
Outputs from Frontiers in Plant Science
#620
of 24,303 outputs
Outputs of similar age
#31,353
of 409,328 outputs
Outputs of similar age from Frontiers in Plant Science
#5
of 500 outputs
Altmetric has tracked 25,257,066 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 92nd percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 24,303 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done particularly well, scoring higher than 97% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 409,328 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 500 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.