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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Rapid Evolution of Manifold CRISPR Systems for Plant Genome Editing
|
|---|---|
| Published in |
Frontiers in Plant Science, November 2016
|
| DOI | 10.3389/fpls.2016.01683 |
| Pubmed ID | |
| Authors |
Levi Lowder, Aimee Malzahn, Yiping Qi |
| Abstract |
Advanced CRISPR-Cas9 based technologies first validated in mammalian cell systems are quickly being adapted for use in plants. These new technologies increase CRISPR-Cas9's utility and effectiveness by diversifying cellular capabilities through expression construct system evolution and enzyme orthogonality, as well as enhanced efficiency through delivery and expression mechanisms. Here, we review the current state of advanced CRISPR-Cas9 and Cpf1 capabilities in plants and cover the rapid evolution of these tools from first generation inducers of double strand breaks for basic genetic manipulations to second and third generation multiplexed systems with myriad functionalities, capabilities, and specialized applications. We offer perspective on how to utilize these tools for currently untested research endeavors and analyze strengths and weaknesses of novel CRISPR systems in plants. Advanced CRISPR functionalities and delivery options demonstrated in plants are primarily reviewed but new technologies just coming to the forefront of CRISPR development, or those on the horizon, are briefly discussed. Topics covered are focused on the expansion of expression and delivery capabilities for CRISPR-Cas9 components and broadening targeting range through orthogonal Cas9 and Cpf1 proteins. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Austria | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 176 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Germany | 2 | 1% |
| United Kingdom | 2 | 1% |
| Netherlands | 1 | <1% |
| Argentina | 1 | <1% |
| Philippines | 1 | <1% |
| Unknown | 169 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 41 | 23% |
| Student > Ph. D. Student | 28 | 16% |
| Student > Master | 26 | 15% |
| Student > Bachelor | 21 | 12% |
| Professor | 9 | 5% |
| Other | 25 | 14% |
| Unknown | 26 | 15% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 90 | 51% |
| Biochemistry, Genetics and Molecular Biology | 46 | 26% |
| Engineering | 3 | 2% |
| Chemistry | 2 | 1% |
| Chemical Engineering | 1 | <1% |
| Other | 4 | 2% |
| Unknown | 30 | 17% |
Attention Score in Context
This research output has an Altmetric Attention Score of 4. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 October 2019.
All research outputs
#7,573,280
of 24,362,308 outputs
Outputs from Frontiers in Plant Science
#4,605
of 22,950 outputs
Outputs of similar age
#106,353
of 312,157 outputs
Outputs of similar age from Frontiers in Plant Science
#75
of 440 outputs
Altmetric has tracked 24,362,308 research outputs across all sources so far. This one has received more attention than most of these and is in the 68th percentile.
So far Altmetric has tracked 22,950 research outputs from this source. They receive a mean Attention Score of 3.9. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 312,157 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 64% of its contemporaries.
We're also able to compare this research output to 440 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 82% of its contemporaries.