Title |
Roles of E3 Ubiquitin-Ligases in Nuclear Protein Homeostasis during Plant Stress Responses
|
---|---|
Published in |
Frontiers in Plant Science, February 2018
|
DOI | 10.3389/fpls.2018.00139 |
Pubmed ID | |
Authors |
Irene Serrano, Laura Campos, Susana Rivas |
Abstract |
Ubiquitination, the reversible protein conjugation with ubiquitin (Ub), is a post-translational modification that enables rapid and specific cellular responses to stimuli without requirement ofde novoprotein synthesis. Although ubiquitination also displays non-proteolytic functions, it often acts as a signal for selective protein degradation through the ubiquitin-proteasome system (UPS). In plants, it has become increasingly apparent that the UPS is a central regulator of many key cellular and physiological processes, including responses to biotic and abiotic stresses. In the nucleus, protein regulationviathe UPS orchestrates gene expression, genome maintenance, and signal transduction. Here, we focus on E3 Ub-ligase proteins as major components of the ubiquitination cascade that confer specificity of substrate recognition. We provide an overview on how they contribute to nuclear proteome plasticity during plant responses to environmental stress signals. |
X Demographics
Geographical breakdown
Country | Count | As % |
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Spain | 1 | 33% |
Switzerland | 1 | 33% |
Unknown | 1 | 33% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 2 | 67% |
Scientists | 1 | 33% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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Unknown | 71 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Ph. D. Student | 17 | 24% |
Researcher | 9 | 13% |
Student > Master | 7 | 10% |
Student > Doctoral Student | 6 | 8% |
Student > Bachelor | 5 | 7% |
Other | 11 | 15% |
Unknown | 16 | 23% |
Readers by discipline | Count | As % |
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Agricultural and Biological Sciences | 27 | 38% |
Biochemistry, Genetics and Molecular Biology | 26 | 37% |
Environmental Science | 1 | 1% |
Immunology and Microbiology | 1 | 1% |
Unknown | 16 | 23% |