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Genome-Wide Association Studies to Identify Loci and Candidate Genes Controlling Kernel Weight and Length in a Historical United States Wheat Population

Overview of attention for article published in Frontiers in Plant Science, August 2018
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Title
Genome-Wide Association Studies to Identify Loci and Candidate Genes Controlling Kernel Weight and Length in a Historical United States Wheat Population
Published in
Frontiers in Plant Science, August 2018
DOI 10.3389/fpls.2018.01045
Pubmed ID
Authors

Sintayehu D. Daba, Priyanka Tyagi, Gina Brown-Guedira, Mohsen Mohammadi

Abstract

Although kernel weight (KW) is a major component of grain yield, its contribution to yield genetic gain during breeding history has been minimal. This highlights an untapped potential for further increases in yield via improving KW. We investigated variation and genetics of KW and kernel length (KL) via genome-wide association studies (GWAS) using a historical and contemporary soft red winter wheat population representing 200 years of selection and breeding history in the United States. The observed changes of KW and KL over time did not show any conclusive trend. The population showed a structure, which was mainly explained by the time and location of germplasm development. Cluster sharing by germplasm from more than one breeding population was suggestive of episodes of germplasm exchange. Using 2 years of field-based phenotyping, we detected 26 quantitative trait loci (QTL) for KW and 27 QTL for KL with -log10(p) > 3.5. The search for candidate genes near the QTL on the wheat genome version IWGSCv1.0 has resulted in over 500 genes. The predicted functions of several of these genes are related to kernel development, photosynthesis, sucrose and starch synthesis, and assimilate remobilization and transport. We also evaluated the effect of allelic polymorphism of genes previously reported for KW and KL by using Kompetitive Allele Specific PCR (KASP) markers. Only TaGW2 showed significant association with KW. Two genes, i.e., TaSus2-2B and TaGS-D1 showed significant association with KL. Further physiological studies are needed to decipher the involvement of these genes in KW and KL development.

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Mendeley readers

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Geographical breakdown

Country Count As %
Unknown 37 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 19%
Researcher 5 14%
Student > Doctoral Student 3 8%
Other 3 8%
Student > Bachelor 2 5%
Other 6 16%
Unknown 11 30%
Readers by discipline Count As %
Agricultural and Biological Sciences 20 54%
Biochemistry, Genetics and Molecular Biology 3 8%
Arts and Humanities 1 3%
Engineering 1 3%
Design 1 3%
Other 0 0%
Unknown 11 30%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 August 2018.
All research outputs
#20,530,891
of 23,100,534 outputs
Outputs from Frontiers in Plant Science
#16,596
of 20,728 outputs
Outputs of similar age
#288,848
of 331,041 outputs
Outputs of similar age from Frontiers in Plant Science
#408
of 471 outputs
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