Title |
A Bioinformatics Pipeline for the Analysis and Target Prediction of RNA Effectors in Bidirectional Communication During Plant–Microbe Interactions
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Published in |
Frontiers in Plant Science, August 2018
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DOI | 10.3389/fpls.2018.01212 |
Pubmed ID | |
Authors |
Silvia Zanini, Ena Šečić, Lukas Jelonek, Karl-Heinz Kogel |
Abstract |
Small RNA (sRNA) molecules are key factors in the communication between hosts and their interacting pathogens, where they function as effectors that can modulate both host defense and microbial virulence/pathogenicity through a mechanism termed cross-kingdom RNA interference (ck-RNAi). Consistent with this recent knowledge, sRNAs and their double-stranded RNA precursor have been adopted to control diseases in crop plants, demonstrating a straight forward application of the new findings to approach agricultural problems. Despite the great interest in natural ck-RNAi, it is astonishing to find just a few additional examples in the literature since the first report was published in 2013. One reason might be that the identification of sRNA effectors is hampered both by technical challenges and lack of routine bioinformatics application strategies. Here, we suggest a practical procedure to find, characterize, and validate sRNA effectors in plant-microbe interaction. The aim of this review is not to present and discuss all possible tools, but to give guidelines toward the best established software available for the analysis. |
X Demographics
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 20% |
Brazil | 1 | 20% |
United States | 1 | 20% |
Germany | 1 | 20% |
Unknown | 1 | 20% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 5 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 56 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 9 | 16% |
Researcher | 6 | 11% |
Student > Master | 6 | 11% |
Student > Bachelor | 5 | 9% |
Student > Doctoral Student | 4 | 7% |
Other | 10 | 18% |
Unknown | 16 | 29% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 17 | 30% |
Biochemistry, Genetics and Molecular Biology | 14 | 25% |
Medicine and Dentistry | 2 | 4% |
Immunology and Microbiology | 2 | 4% |
Business, Management and Accounting | 1 | 2% |
Other | 3 | 5% |
Unknown | 17 | 30% |