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Task-Dependent Modulation of Effective Connectivity within the Default Mode Network

Overview of attention for article published in Frontiers in Psychology, January 2012
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Title
Task-Dependent Modulation of Effective Connectivity within the Default Mode Network
Published in
Frontiers in Psychology, January 2012
DOI 10.3389/fpsyg.2012.00206
Pubmed ID
Authors

Baojuan Li, Xiang Wang, Shuqiao Yao, Dewen Hu, Karl Friston

Abstract

The default mode network (DMN) has recently attracted widespread interest. Previous studies have found that task-related processing can induce deactivation and changes in the functional connectivity of this network. However, it remains unclear how tasks modulate the underlying effective connectivity within the DMN. Using recent advances in dynamic causal modeling (DCM), we investigated the modulatory effect of (gender judgment) task performance on directed connectivity within the DMN. Sixteen healthy subjects were scanned twice: at rest and while performing a gender judgment task. Group independent component analysis was used to identify independent spatial components. Four subject-specific regions of interest (ROIs) were defined according to the ensuing default mode component: the posterior cingulate cortex, the left lateral parietal cortex, the right lateral parietal cortex, and the medial prefrontal cortex. Effective connectivity among these regions was then characterized with stochastic DCM, revealing enhanced (extrinsic) between region connectivity within the DMN during task sessions - and a universal decrease in (intrinsic) self-inhibition - relative to resting sessions. These results suggest a distributed but systematic modulatory effect of cognitive and attentional set on the effective connectivity subtending the DMN: an effect that increases its sensitivity to inputs and may optimize distributed processing during task performance.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 137 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 3 2%
United Kingdom 2 1%
United States 2 1%
Austria 1 <1%
Japan 1 <1%
Switzerland 1 <1%
Unknown 127 93%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 29 21%
Researcher 28 20%
Student > Master 15 11%
Student > Doctoral Student 9 7%
Student > Bachelor 8 6%
Other 30 22%
Unknown 18 13%
Readers by discipline Count As %
Psychology 33 24%
Neuroscience 30 22%
Medicine and Dentistry 18 13%
Agricultural and Biological Sciences 10 7%
Engineering 8 6%
Other 12 9%
Unknown 26 19%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 02 June 2012.
All research outputs
#19,631,015
of 24,143,470 outputs
Outputs from Frontiers in Psychology
#24,116
of 32,434 outputs
Outputs of similar age
#203,205
of 251,134 outputs
Outputs of similar age from Frontiers in Psychology
#380
of 482 outputs
Altmetric has tracked 24,143,470 research outputs across all sources so far. This one is in the 10th percentile – i.e., 10% of other outputs scored the same or lower than it.
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