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Count on dopamine: influences of COMT polymorphisms on numerical cognition

Overview of attention for article published in Frontiers in Psychology, January 2013
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Title
Count on dopamine: influences of COMT polymorphisms on numerical cognition
Published in
Frontiers in Psychology, January 2013
DOI 10.3389/fpsyg.2013.00531
Pubmed ID
Authors

Annelise Júlio-Costa, Andressa M. Antunes, Júlia B. Lopes-Silva, Bárbara C. Moreira, Gabrielle S. Vianna, Guilherme Wood, Maria R. S. Carvalho, Vitor G. Haase

Abstract

Catechol-O-methyltransferase (COMT) is an enzyme that is particularly important for the metabolism of dopamine. Functional polymorphisms of COMT have been implicated in working memory and numerical cognition. This is an exploratory study that aims at investigating associations between COMT polymorphisms, working memory, and numerical cognition. Elementary school children from 2th to 6th grades were divided into two groups according to their COMT val158met polymorphism [homozygous for valine allele (n = 61) vs. heterozygous plus methionine homozygous children or met+ group (n = 94)]. Both groups were matched for age and intelligence. Working memory was assessed through digit span and Corsi blocks. Symbolic numerical processing was assessed through transcoding and single-digit word problem tasks. Non-symbolic magnitude comparison and estimation tasks were used to assess number sense. Between-group differences were found in symbolic and non-symbolic numerical tasks, but not in working memory tasks. Children in the met+ group showed better performance in all numerical tasks while val homozygous children presented slower development of non-symbolic magnitude representations. These results suggest COMT-related dopaminergic modulation may be related not only to working memory, as found in previous studies, but also to the development of magnitude processing and magnitude representations.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 65 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Mexico 1 2%
United States 1 2%
Portugal 1 2%
Denmark 1 2%
Unknown 61 94%

Demographic breakdown

Readers by professional status Count As %
Student > Master 14 22%
Student > Bachelor 10 15%
Researcher 7 11%
Student > Ph. D. Student 6 9%
Student > Postgraduate 4 6%
Other 10 15%
Unknown 14 22%
Readers by discipline Count As %
Psychology 22 34%
Medicine and Dentistry 6 9%
Neuroscience 6 9%
Agricultural and Biological Sciences 6 9%
Biochemistry, Genetics and Molecular Biology 4 6%
Other 7 11%
Unknown 14 22%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 16 August 2013.
All research outputs
#16,917,702
of 24,943,708 outputs
Outputs from Frontiers in Psychology
#20,435
of 33,669 outputs
Outputs of similar age
#193,964
of 292,957 outputs
Outputs of similar age from Frontiers in Psychology
#699
of 969 outputs
Altmetric has tracked 24,943,708 research outputs across all sources so far. This one is in the 31st percentile – i.e., 31% of other outputs scored the same or lower than it.
So far Altmetric has tracked 33,669 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.1. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 292,957 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 33rd percentile – i.e., 33% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 969 others from the same source and published within six weeks on either side of this one. This one is in the 26th percentile – i.e., 26% of its contemporaries scored the same or lower than it.