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Default mode network alterations during implicit emotional faces processing in first-episode, treatment-naive major depression patients

Overview of attention for article published in Frontiers in Psychology, August 2015
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Title
Default mode network alterations during implicit emotional faces processing in first-episode, treatment-naive major depression patients
Published in
Frontiers in Psychology, August 2015
DOI 10.3389/fpsyg.2015.01198
Pubmed ID
Authors

Huqing Shi, Xiang Wang, Jinyao Yi, Xiongzhao Zhu, Xiaocui Zhang, Juan Yang, Shuqiao Yao

Abstract

Previous studies have focused on resting-state default mode network (DMN) alterations in the development and maintenance of depression; however, only a few studies have addressed DMN changes during task-related processing and their results are inconsistent. Therefore, we explored DMN patterns in young adult patients with first-episode, treatment-naïve major depressive disorder (MDD) performing an implicit emotional processing task. Patients with MDD (N = 29) and healthy controls (N = 33) were subjected to functional magnetic resonance imaging (fMRI) at rest and while performing a gender judgment task. Group independent component analysis (ICA) was used to identify DMN component under task state for both groups. The DMN of participants with MDD had decreased functional connectivity in bilateral prefrontal areas compared to controls. Right prefrontal gyrus connectivity for MDD patients correlated negatively with scores on maladaptive scales of the Cognitive Emotion Regulation Questionnaire (CERQ). Our findings suggest that depressed people have altered DMN patterns during implicit emotional processing, which might be related to impaired internal monitoring and emotional regulation ability.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 62 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 62 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 12 19%
Student > Ph. D. Student 10 16%
Student > Bachelor 7 11%
Student > Doctoral Student 5 8%
Researcher 5 8%
Other 5 8%
Unknown 18 29%
Readers by discipline Count As %
Psychology 26 42%
Neuroscience 9 15%
Medicine and Dentistry 3 5%
Mathematics 1 2%
Chemistry 1 2%
Other 1 2%
Unknown 21 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 August 2015.
All research outputs
#20,286,650
of 22,821,814 outputs
Outputs from Frontiers in Psychology
#24,087
of 29,780 outputs
Outputs of similar age
#221,549
of 264,494 outputs
Outputs of similar age from Frontiers in Psychology
#538
of 558 outputs
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