Title |
Parasomnias and Antidepressant Therapy: A Review of the Literature
|
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Published in |
Frontiers in Psychiatry, January 2011
|
DOI | 10.3389/fpsyt.2011.00071 |
Pubmed ID | |
Authors |
Lara Kierlin, Michael R. Littner |
Abstract |
There exists a varying level of evidence linking the use of antidepressant medication to the parasomnias, ranging from larger, more comprehensive studies in the area of REM sleep behavior disorder to primarily case reports in the NREM parasomnias. As such, practice guidelines are lacking regarding specific direction to the clinician who may be faced with a patient who has developed a parasomnia that appears to be temporally related to use of an antidepressant. In general, knowledge of the mechanisms of action of the medications, particularly with regard to the impact on sleep architecture, can provide some guidance. There is a potential for selective serotonin reuptake inhibitors, tricyclic antidepressants, and serotonin-norepinephrine reuptake inhibitors to suppress REM, as well as the anticholinergic properties of the individual drugs to further disturb normal sleep architecture. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
United States | 2 | 33% |
Canada | 1 | 17% |
Japan | 1 | 17% |
Unknown | 2 | 33% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 6 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 68 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Researcher | 9 | 13% |
Student > Ph. D. Student | 8 | 12% |
Student > Master | 7 | 10% |
Other | 6 | 9% |
Student > Bachelor | 5 | 7% |
Other | 15 | 22% |
Unknown | 18 | 26% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 22 | 32% |
Psychology | 7 | 10% |
Neuroscience | 5 | 7% |
Agricultural and Biological Sciences | 4 | 6% |
Biochemistry, Genetics and Molecular Biology | 1 | 1% |
Other | 4 | 6% |
Unknown | 25 | 37% |