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Low- vs High-Frequency Repetitive Transcranial Magnetic Stimulation as an Add-On Treatment for Refractory Depression

Overview of attention for article published in Frontiers in Psychiatry, January 2012
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Title
Low- vs High-Frequency Repetitive Transcranial Magnetic Stimulation as an Add-On Treatment for Refractory Depression
Published in
Frontiers in Psychiatry, January 2012
DOI 10.3389/fpsyt.2012.00013
Pubmed ID
Authors

Julien Eche, Marine Mondino, Frederic Haesebaert, Mohamed Saoud, Emmanuel Poulet, Jerome Brunelin

Abstract

Objectives: Repetitive transcranial magnetic stimulation (rTMS) seems to be effective as an antidepressant, however, some confusion remains about the best parameters to apply and the efficacy of its association with pharmacological antidepressant treatments. Method: In a single blind randomized study 14 patients with unipolar resistant depression to one antidepressant treatment were enrolled to receive, in combination with venlafaxine (150 mg), either 20 sessions of 10 Hz rTMS (2000 pulses per session) applied over the left dorsolateral prefrontal cortex (DLPFC) or 20 sessions of 1 Hz rTMS (120 stimulations per sessions) applied over the right DLPFC. Results: A similar antidepressant effect was observed in both groups with a comparable antidepressant delay of action (2 weeks) and a comparable number of responders (MADRS < 15) after 4 weeks of daily rTMS sessions (66 vs 50%). Conclusion: Low- and high- frequency rTMS seems to be effective as an add-on treatment to venlafaxine as monotherapy in pharmacological refractory major depression (stage 1). Due to its short duration (one session of 1 Hz rTMS lasts 4 min vs 16 for 10 Hz rTMS) and its safety, low frequency rTMS may be a useful alternative treatment for patients with refractory depression.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 92 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 1%
Germany 1 1%
Canada 1 1%
Unknown 89 97%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 15 16%
Researcher 13 14%
Student > Master 11 12%
Student > Postgraduate 9 10%
Other 6 7%
Other 20 22%
Unknown 18 20%
Readers by discipline Count As %
Medicine and Dentistry 21 23%
Psychology 16 17%
Neuroscience 11 12%
Agricultural and Biological Sciences 10 11%
Engineering 3 3%
Other 7 8%
Unknown 24 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 20 March 2013.
All research outputs
#13,366,719
of 22,675,759 outputs
Outputs from Frontiers in Psychiatry
#4,035
of 9,789 outputs
Outputs of similar age
#146,660
of 244,088 outputs
Outputs of similar age from Frontiers in Psychiatry
#45
of 90 outputs
Altmetric has tracked 22,675,759 research outputs across all sources so far. This one is in the 39th percentile – i.e., 39% of other outputs scored the same or lower than it.
So far Altmetric has tracked 9,789 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.4. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 244,088 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 38th percentile – i.e., 38% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 90 others from the same source and published within six weeks on either side of this one. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.