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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Deep Brain Stimulation as a Tool for Improving Cognitive Functioning in Alzheimer’s Dementia: A Systematic Review
|
|---|---|
| Published in |
Frontiers in Psychiatry, January 2013
|
| DOI | 10.3389/fpsyt.2013.00159 |
| Pubmed ID | |
| Authors |
Katja Hardenacke, Elena Shubina, Christian Philipp Bührle, Alexandra Zapf, Doris Lenartz, Joachim Klosterkötter, Veerle Visser-Vandewalle, Jens Kuhn |
| Abstract |
Deep brain stimulation (DBS) is an established, in selected cases therapeutically effective, non-lesional treatment method delivering current rectangular pulses into dysfunctional brain structures via chronically implanted stimulation electrodes. DBS is a recognized method applied in movement disorders and is increasingly evaluated as a possible therapeutic option for psychiatric diseases such as refractory obsessive-compulsive disorders, Gilles de la Tourette syndrome, major depression, and substance-related addiction. Latest research indicates that DBS may be a method for improving cognitive functions in Alzheimer's dementia (AD). Translational data in healthy and AD animals appear to support this notion. Nevertheless, many aspects remain unclear, particularly with regard to the optimal target structure. The objective of this review is to present a systematic overview regarding published research on DBS and cognitive functioning in animal and human studies as well as to provide a systematic overview of the feasibility and efficacy of the treatment. We describe three studies investigating the effects of DBS in patients with dementia, using either the fornix or the nucleus basalis of Meynert (NBM) as a target. In total, we identified 25 animal studies with 10 brain structures being targeted: fornix, NBM, anterior caudate nucleus, dorsal striatum, anterior thalamic nucleus, midline thalamic nuclei, central thalamus, lateral hypothalamus, hippocampus (entorhinal cortex, perforant path), and amygdala. Considering the wide and diverse spectrum of targets, we add to this review a supposition about possible underlying mechanisms of operation and recommendations for further research. |
X Demographics
The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 50% |
| Unknown | 1 | 50% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 50% |
| Practitioners (doctors, other healthcare professionals) | 1 | 50% |
Mendeley readers
The data shown below were compiled from readership statistics for 170 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 2 | 1% |
| France | 2 | 1% |
| Spain | 2 | 1% |
| United Kingdom | 1 | <1% |
| Germany | 1 | <1% |
| China | 1 | <1% |
| United States | 1 | <1% |
| Unknown | 160 | 94% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 30 | 18% |
| Student > Ph. D. Student | 29 | 17% |
| Student > Bachelor | 21 | 12% |
| Student > Master | 17 | 10% |
| Student > Doctoral Student | 9 | 5% |
| Other | 36 | 21% |
| Unknown | 28 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 36 | 21% |
| Psychology | 28 | 16% |
| Neuroscience | 25 | 15% |
| Agricultural and Biological Sciences | 17 | 10% |
| Engineering | 7 | 4% |
| Other | 17 | 10% |
| Unknown | 40 | 24% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 September 2014.
All research outputs
#15,286,644
of 22,733,113 outputs
Outputs from Frontiers in Psychiatry
#5,726
of 9,853 outputs
Outputs of similar age
#181,576
of 280,780 outputs
Outputs of similar age from Frontiers in Psychiatry
#139
of 185 outputs
Altmetric has tracked 22,733,113 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 9,853 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.4. This one is in the 38th percentile – i.e., 38% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 280,780 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 25th percentile – i.e., 25% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 185 others from the same source and published within six weeks on either side of this one. This one is in the 21st percentile – i.e., 21% of its contemporaries scored the same or lower than it.