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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Stress, Inflammation, and Cellular Vulnerability during Early Stages of Affective Disorders: Biomarker Strategies and Opportunities for Prevention and Intervention
|
|---|---|
| Published in |
Frontiers in Psychiatry, April 2014
|
| DOI | 10.3389/fpsyt.2014.00034 |
| Pubmed ID | |
| Authors |
Adam J. Walker, Yesul Kim, J. Blair Price, Rajas P. Kale, Jane A. McGillivray, Michael Berk, Susannah J. Tye |
| Abstract |
The mood disorder prodrome is conceptualized as a symptomatic, but not yet clinically diagnosable stage of an affective disorder. Although a growing area, more focused research is needed in the pediatric population to better characterize psychopathological symptoms and biological markers that can reliably identify this very early stage in the evolution of mood disorder pathology. Such information will facilitate early prevention and intervention, which has the potential to affect a person's disease course. This review focuses on the prodromal characteristics, risk factors, and neurobiological mechanisms of mood disorders. In particular, we consider the influence of early-life stress, inflammation, and allostatic load in mediating neural mechanisms of neuroprogression. These inherently modifiable factors have known neuroadaptive and neurodegenerative implications, and consequently may provide useful biomarker targets. Identification of these factors early in the course of the disease will accordingly allow for the introduction of early interventions which augment an individual's capacity for psychological resilience through maintenance of synaptic integrity and cellular resilience. A targeted and complementary approach to boosting both psychological and physiological resilience simultaneously during the prodromal stage of mood disorder pathology has the greatest promise for optimizing the neurodevelopmental potential of those individuals at risk of disabling mood disorders. |
X Demographics
The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 33% |
| United Kingdom | 1 | 33% |
| Unknown | 1 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 3 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 156 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | <1% |
| United States | 1 | <1% |
| Portugal | 1 | <1% |
| Australia | 1 | <1% |
| Unknown | 152 | 97% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 28 | 18% |
| Researcher | 25 | 16% |
| Student > Bachelor | 15 | 10% |
| Other | 14 | 9% |
| Student > Master | 13 | 8% |
| Other | 42 | 27% |
| Unknown | 19 | 12% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 38 | 24% |
| Psychology | 28 | 18% |
| Neuroscience | 18 | 12% |
| Agricultural and Biological Sciences | 12 | 8% |
| Biochemistry, Genetics and Molecular Biology | 7 | 4% |
| Other | 21 | 13% |
| Unknown | 32 | 21% |
Attention Score in Context
This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 July 2015.
All research outputs
#2,869,806
of 22,753,345 outputs
Outputs from Frontiers in Psychiatry
#1,502
of 9,896 outputs
Outputs of similar age
#30,421
of 228,038 outputs
Outputs of similar age from Frontiers in Psychiatry
#9
of 33 outputs
Altmetric has tracked 22,753,345 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 9,896 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.4. This one has done well, scoring higher than 84% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 228,038 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 86% of its contemporaries.
We're also able to compare this research output to 33 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 69% of its contemporaries.