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Network Based Statistical Analysis Detects Changes Induced by Continuous Theta-Burst Stimulation on Brain Activity at Rest

Overview of attention for article published in Frontiers in Psychiatry, August 2014
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Title
Network Based Statistical Analysis Detects Changes Induced by Continuous Theta-Burst Stimulation on Brain Activity at Rest
Published in
Frontiers in Psychiatry, August 2014
DOI 10.3389/fpsyt.2014.00097
Pubmed ID
Authors

Chiara Mastropasqua, Marco Bozzali, Viviana Ponzo, Giovanni Giulietti, Carlo Caltagirone, Mara Cercignani, Giacomo Koch

Abstract

We combined continuous theta-burst stimulation (cTBS) and resting state (RS)-fMRI approaches to investigate changes in functional connectivity (FC) induced by right dorsolateral prefrontal cortex (DLPFC)-cTBS at rest in a group of healthy subjects. Seed-based fMRI analysis revealed a specific pattern of correlation between the right prefrontal cortex and several brain regions: based on these results, we defined a 29-node network to assess changes in each network connection before and after, respectively, DLPFC-cTBS and sham sessions. A decrease of correlation between the right prefrontal cortex and right parietal cortex (Brodmann areas 46 and 40, respectively) was detected after cTBS, while no significant result was found when analyzing sham-session data. To our knowledge, this is the first study that demonstrates within-subject changes in FC induced by cTBS applied on prefrontal area. The possibility to induce selective changes in a specific region without interfering with functionally correlated area could have several implications for the study of functional properties of the brain, and for the emerging therapeutic strategies based on transcranial stimulation.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 51 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Germany 1 2%
Unknown 50 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 13 25%
Researcher 8 16%
Student > Master 5 10%
Student > Bachelor 4 8%
Student > Doctoral Student 3 6%
Other 10 20%
Unknown 8 16%
Readers by discipline Count As %
Neuroscience 13 25%
Psychology 8 16%
Medicine and Dentistry 6 12%
Agricultural and Biological Sciences 5 10%
Engineering 2 4%
Other 3 6%
Unknown 14 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 August 2014.
All research outputs
#18,375,478
of 22,759,618 outputs
Outputs from Frontiers in Psychiatry
#6,811
of 9,899 outputs
Outputs of similar age
#164,198
of 230,115 outputs
Outputs of similar age from Frontiers in Psychiatry
#50
of 58 outputs
Altmetric has tracked 22,759,618 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
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