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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Role of the Endogenous Cannabinoid System in Nicotine Addiction: Novel Insights
|
|---|---|
| Published in |
Frontiers in Psychiatry, January 2015
|
| DOI | 10.3389/fpsyt.2015.00041 |
| Pubmed ID | |
| Authors |
Islam Hany Gamaleddin, Jose M. Trigo, Aliou B. Gueye, Alexander Zvonok, Alexandros Makriyannis, Steven R. Goldberg, Bernard Le Foll |
| Abstract |
Several lines of evidence have shown that the endogenous cannabinoids are implicated in several neuropsychiatric diseases. Notably, preclinical and human clinical studies have shown a pivotal role of the cannabinoid system in nicotine addiction. The CB1 receptor inverse agonist/antagonist rimonabant (also known as SR141716) was effective to decrease nicotine-taking and nicotine-seeking in rodents, as well as the elevation of dopamine induced by nicotine in brain reward area. Rimonabant has been shown to improve the ability of smokers to quit smoking in randomized clinical trials. However, rimonabant was removed from the market due to increased risk of psychiatric side-effects observed in humans. Recently, other components of the endogenous cannabinoid system have been explored. Here, we present the recent advances on the understanding of the role of the different components of the cannabinoid system on nicotine's effects. Those recent findings suggest possible alternative ways of modulating the cannabinoid system that could have implication for nicotine dependence treatment. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Canada | 1 | 17% |
| United Kingdom | 1 | 17% |
| Switzerland | 1 | 17% |
| United States | 1 | 17% |
| Unknown | 2 | 33% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 5 | 83% |
| Practitioners (doctors, other healthcare professionals) | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 87 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 1% |
| Germany | 1 | 1% |
| Unknown | 85 | 98% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 19 | 22% |
| Researcher | 8 | 9% |
| Student > Master | 8 | 9% |
| Student > Bachelor | 8 | 9% |
| Other | 7 | 8% |
| Other | 18 | 21% |
| Unknown | 19 | 22% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 18 | 21% |
| Psychology | 11 | 13% |
| Medicine and Dentistry | 10 | 11% |
| Pharmacology, Toxicology and Pharmaceutical Science | 7 | 8% |
| Neuroscience | 6 | 7% |
| Other | 13 | 15% |
| Unknown | 22 | 25% |
Attention Score in Context
This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 September 2022.
All research outputs
#6,162,734
of 24,501,737 outputs
Outputs from Frontiers in Psychiatry
#2,827
of 11,754 outputs
Outputs of similar age
#78,096
of 362,511 outputs
Outputs of similar age from Frontiers in Psychiatry
#20
of 56 outputs
Altmetric has tracked 24,501,737 research outputs across all sources so far. This one has received more attention than most of these and is in the 74th percentile.
So far Altmetric has tracked 11,754 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.0. This one has done well, scoring higher than 75% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 362,511 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 56 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.