Title |
Inflammation, Stress Response, and Redox Dysregulation Biomarkers: Clinical Outcomes and Pharmacological Implications for Psychosis
|
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Published in |
Frontiers in Psychiatry, October 2017
|
DOI | 10.3389/fpsyt.2017.00203 |
Pubmed ID | |
Authors |
Stefania Schiavone, Luigia Trabace |
Abstract |
In recent years, several studies claiming the finding of a specific biomarker for the identification of the "high-risk state" to develop psychosis, first psychotic episode, as well as the prediction of the individual response to antipsychotics have been published. Together with genetic reports, numerous publications in this field have been focused on inflammation and stress response blood biomarkers, as well as on indicators of redox dysregulation. In this review, we focus on human studies found in PubMed from January 1(st) 2010 to January 31(st) 2017, describing the clinical use of these biomarkers to detect the "premorbid" psychotic state and early phases of the disease. Their pharmacological implications in predicting and monitoring the individual response to antipsychotic medication is also discussed. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Switzerland | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 46 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Ph. D. Student | 7 | 15% |
Researcher | 6 | 13% |
Student > Master | 6 | 13% |
Other | 4 | 9% |
Student > Bachelor | 3 | 7% |
Other | 10 | 22% |
Unknown | 10 | 22% |
Readers by discipline | Count | As % |
---|---|---|
Medicine and Dentistry | 12 | 26% |
Biochemistry, Genetics and Molecular Biology | 5 | 11% |
Psychology | 4 | 9% |
Agricultural and Biological Sciences | 3 | 7% |
Chemistry | 2 | 4% |
Other | 6 | 13% |
Unknown | 14 | 30% |