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Metabolic Barriers to Weight Gain in Patients With Anorexia Nervosa: A Young Adult Case Report

Overview of attention for article published in Frontiers in Psychiatry, May 2018
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (78th percentile)
  • Above-average Attention Score compared to outputs of the same age and source (59th percentile)

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3 X users
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1 Facebook page
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1 YouTube creator

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Title
Metabolic Barriers to Weight Gain in Patients With Anorexia Nervosa: A Young Adult Case Report
Published in
Frontiers in Psychiatry, May 2018
DOI 10.3389/fpsyt.2018.00199
Pubmed ID
Authors

Verena Haas, Andreas Stengel, Anja Mähler, Gabriele Gerlach, Celine Lehmann, Michael Boschmann, Martina de Zwaan, Stephan Herpertz

Abstract

Background: Over-proportionally high energy requirements in some patients with anorexia nervosa (AN) have been reported, but their exact origin remains unclear. Objective: To objectively measure metabolic alterations in an AN patient with high energy requirements as judged by clinical observation. Materials and Methods: We present the case of a young woman with AN (index patient, IP; 19 years, admission BMI 13.9 kg/m2). After 3 months of treatment at BMI 17.4 kg/m2, we assessed her resting energy expenditure (REE), respiratory exchange ratio (RER), diet-induced thermogenesis (DIT), seated non-exercise physical activity (NEPA in Volt by infrared sensors), and exercise activity thermogenesis (EAT) in a metabolic chamber; body composition (bioimpedance analysis), energy intake (15d-food protocol), physical activity (accelerometry) and endocrine parameters. The IP was compared for REE, RER, DIT and seated NEPA to six AN patients (AN-C) and four healthy women (HC-1), and for EAT to another six healthy women (HC-2). Results: Our IP showed high REE (110% of predicted REE according to Harris & Benedict) and high seated NEPA (47% increase over AN-C, 40% over HC-1), whereas DIT (IP: 78 vs. HC-1: 145 ± 51 kJ/180 min) and EAT (IP: 157 vs. HC-2: 235 ± 30 kJ/30 min) were low, when compared with HC. The other AN patients showed a lower REE (AN: 87 ± 2% vs. HC: 97 ± 2% predicted) at increased DIT (AN: 187 ± 91 vs. HC: 145 ± 51 kJ/180 min) when compared with HC. RER of the IP was low (IP: 0.72 vs. 0.77 in AN-C; 0.77 in HC-1 and 0.80 in HC-2). Conclusions: Complex and variable disturbances of energy metabolism might exist in a subgroup of patients with AN during refeeding, which could lead to unexpectedly high energy requirements. Future studies need to confirm the existence, and investigate the characteristics and prevalence of this subgroup. Clinical trial Registry number: NCT02087280, https://www.clinicaltrials.gov/.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 46 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 46 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 6 13%
Student > Ph. D. Student 5 11%
Student > Doctoral Student 4 9%
Student > Bachelor 3 7%
Student > Postgraduate 3 7%
Other 7 15%
Unknown 18 39%
Readers by discipline Count As %
Medicine and Dentistry 7 15%
Psychology 7 15%
Nursing and Health Professions 5 11%
Sports and Recreations 3 7%
Agricultural and Biological Sciences 2 4%
Other 1 2%
Unknown 21 46%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 9. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 18 May 2022.
All research outputs
#3,649,644
of 23,035,022 outputs
Outputs from Frontiers in Psychiatry
#1,862
of 10,154 outputs
Outputs of similar age
#72,001
of 329,109 outputs
Outputs of similar age from Frontiers in Psychiatry
#70
of 177 outputs
Altmetric has tracked 23,035,022 research outputs across all sources so far. Compared to these this one has done well and is in the 84th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 10,154 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one has done well, scoring higher than 81% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,109 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 78% of its contemporaries.
We're also able to compare this research output to 177 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 59% of its contemporaries.