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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Revisiting the Role of Eotaxin-1/CCL11 in Psychiatric Disorders
|
|---|---|
| Published in |
Frontiers in Psychiatry, June 2018
|
| DOI | 10.3389/fpsyt.2018.00241 |
| Pubmed ID | |
| Authors |
Antonio L. Teixeira, Clarissa S. Gama, Natalia P. Rocha, Mauro M. Teixeira |
| Abstract |
Eotaxin-1/CCL11 is a chemokine originally implicated in the selective recruitment of eosinophils into inflammatory sites during allergic reactions, being thoroughly investigated in asthma, allergic rhinitis, and other eosinophil-related conditions. Eotaxin-1/CCL11 is also involved with a skewed immune response toward a type-2 (Th2) profile. In addition to its role in immune response, recent studies have shown that eotaxin-1/CCL11 is associated with aging, neurogenesis and neurodegeneration, being able to influence neural progenitor cells, and microglia. Increased circulating levels of eotaxin-1/CCL11 have been described in major psychiatric disorders (schizophrenia, bipolar disorder, major depression), sometimes correlating with the severity of psychopathological and cognitive parameters. As similar findings have been reported in neurodegenerative conditions such as Alzheimer's disease, it has been hypothesized that mechanisms involving eotaxin-1/CCL11 signaling may underlie the "accelerated aging" profile commonly linked to psychiatric disorders. Future studies must determine whether eotaxin-1/CCL11 can be regarded as a prognostic biomarker and/or as therapeutic target for resistant/progressive cases. |
X Demographics
The data shown below were collected from the profiles of 8 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 13% |
| Switzerland | 1 | 13% |
| Unknown | 6 | 75% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 7 | 88% |
| Practitioners (doctors, other healthcare professionals) | 1 | 13% |
Mendeley readers
The data shown below were compiled from readership statistics for 130 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 130 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 21 | 16% |
| Student > Bachelor | 17 | 13% |
| Student > Ph. D. Student | 17 | 13% |
| Student > Master | 16 | 12% |
| Student > Doctoral Student | 8 | 6% |
| Other | 13 | 10% |
| Unknown | 38 | 29% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 16 | 12% |
| Biochemistry, Genetics and Molecular Biology | 15 | 12% |
| Neuroscience | 14 | 11% |
| Immunology and Microbiology | 6 | 5% |
| Psychology | 6 | 5% |
| Other | 26 | 20% |
| Unknown | 47 | 36% |
Attention Score in Context
This research output has an Altmetric Attention Score of 12. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 December 2022.
All research outputs
#2,880,439
of 25,483,400 outputs
Outputs from Frontiers in Psychiatry
#1,716
of 12,754 outputs
Outputs of similar age
#56,891
of 342,153 outputs
Outputs of similar age from Frontiers in Psychiatry
#52
of 175 outputs
Altmetric has tracked 25,483,400 research outputs across all sources so far. Compared to these this one has done well and is in the 88th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 12,754 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 11.4. This one has done well, scoring higher than 86% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 342,153 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 83% of its contemporaries.
We're also able to compare this research output to 175 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 70% of its contemporaries.