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Biological Mechanisms of Cancer-Induced Depression

Overview of attention for article published in Frontiers in Psychiatry, July 2018
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Title
Biological Mechanisms of Cancer-Induced Depression
Published in
Frontiers in Psychiatry, July 2018
DOI 10.3389/fpsyt.2018.00299
Pubmed ID
Authors

Kimberly Young, Gurmit Singh

Abstract

Patients with cancer are more likely to develop depression than the general population, which negatively impacts their quality of life and prognosis. In order to identify effective antidepressants catered toward cancer patients, the biology of depression in the context of cancer must be well-understood. Many theories have emerged postulating the mechanisms underlying the development of depressive disorder. Here, we review the role inflammation, a hyperactive hypothalamic-pituitary-adrenal (HPA) axis, and glutamate excitotoxicity may play in cancer-induced depression. Hopefully, novel therapeutics targeting these dysregulated pathways may be potent in ameliorating depressive symptoms in the cancer population.

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The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 90 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 90 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 14 16%
Student > Master 8 9%
Student > Doctoral Student 6 7%
Other 5 6%
Researcher 5 6%
Other 14 16%
Unknown 38 42%
Readers by discipline Count As %
Medicine and Dentistry 18 20%
Neuroscience 8 9%
Biochemistry, Genetics and Molecular Biology 8 9%
Nursing and Health Professions 4 4%
Psychology 3 3%
Other 6 7%
Unknown 43 48%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 July 2018.
All research outputs
#15,536,861
of 23,090,520 outputs
Outputs from Frontiers in Psychiatry
#5,870
of 10,211 outputs
Outputs of similar age
#208,316
of 326,346 outputs
Outputs of similar age from Frontiers in Psychiatry
#130
of 175 outputs
Altmetric has tracked 23,090,520 research outputs across all sources so far. This one is in the 22nd percentile – i.e., 22% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,211 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.5. This one is in the 39th percentile – i.e., 39% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 326,346 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 175 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.