Title |
Genetic Associations with Plasma B12, B6, and Folate Levels in an Ischemic Stroke Population from the Vitamin Intervention for Stroke Prevention (VISP) Trial
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Published in |
Frontiers in Public Health, August 2014
|
DOI | 10.3389/fpubh.2014.00112 |
Pubmed ID | |
Authors |
Keith L. Keene, Wei-Min Chen, Fang Chen, Stephen R. Williams, Stacey D. Elkhatib, Fang-Chi Hsu, Josyf C. Mychaleckyj, Kimberly F. Doheny, Elizabeth W. Pugh, Hua Ling, Cathy C. Laurie, Stephanie M. Gogarten, Ebony B. Madden, Bradford B. Worrall, Michele M. Sale |
Abstract |
B vitamins play an important role in homocysteine metabolism, with vitamin deficiencies resulting in increased levels of homocysteine and increased risk for stroke. We performed a genome-wide association study (GWAS) in 2,100 stroke patients from the Vitamin Intervention for Stroke Prevention (VISP) trial, a clinical trial designed to determine whether the daily intake of high-dose folic acid, vitamins B6, and B12 reduce recurrent cerebral infarction. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Switzerland | 1 | 100% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 57 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Student > Bachelor | 11 | 19% |
Student > Ph. D. Student | 9 | 16% |
Researcher | 5 | 9% |
Student > Postgraduate | 5 | 9% |
Student > Master | 5 | 9% |
Other | 12 | 21% |
Unknown | 10 | 18% |
Readers by discipline | Count | As % |
---|---|---|
Agricultural and Biological Sciences | 12 | 21% |
Biochemistry, Genetics and Molecular Biology | 12 | 21% |
Medicine and Dentistry | 11 | 19% |
Nursing and Health Professions | 4 | 7% |
Pharmacology, Toxicology and Pharmaceutical Science | 2 | 4% |
Other | 4 | 7% |
Unknown | 12 | 21% |