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Study Protocol on Hormonal Mediation of Exercise on Cognition, Stress and Immunity (PRO-HMECSI): Effects of Different Exercise Programmes in Institutionalized Elders

Overview of attention for article published in Frontiers in Public Health, June 2016
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Title
Study Protocol on Hormonal Mediation of Exercise on Cognition, Stress and Immunity (PRO-HMECSI): Effects of Different Exercise Programmes in Institutionalized Elders
Published in
Frontiers in Public Health, June 2016
DOI 10.3389/fpubh.2016.00133
Pubmed ID
Authors

Ana Maria Teixeira, José Pedro Ferreira, Eef Hogervorst, Margarida Ferreira Braga, Stephan Bandelow, Luís Rama, António Figueiredo, Maria João Campos, Guilherme Eustáquio Furtado, Matheus Uba Chupel, Filipa Martins Pedrosa

Abstract

Physical activity (PA) in elders has been shown to have positive effects on a plethora of chronic diseases and to improve immunity, mental health, and cognition. Chronic stress has also been shown to have immuno-suppressive effects and to accelerate immunosenescence. Exercise could be a significant factor in ameliorating the deleterious effects of chronic stress, but variables such as the type, intensity, and frequency of exercise that should be performed in order to effectively reduce the stress burden need to be defined clearly. PRO-HMECSI will allow us to investigate which hormonal and immunological parameters are able to mediate the effects of exercise on mucosal immunity, psychological/biological stress, and cognitive functioning in older people. Phase I consists of an observational cross-sectional study that compares elders groups (n = 223, >65 years) by functional fitness levels aiming to identify biomarkers involved in maintaining immune and mental health. Neuroendocrine and immune biomarkers of stress, psychological well-being related to mental health, neurocognitive function, functional fitness, and daily PA will be evaluated. Phase II consists of a 28-week intervention in elders with mild cognitive impairment (MCI) profile (n = 149, >65 years, divided in three groups of exercise and one control group), aiming to investigate whether the positive effect of three different types of chair-based exercise programs on physical and psychological health is mediated by an optimal endocrine environment. Primary outcomes are measures of cognitive function and global health. Secondary outcomes include the evaluation the other dimensions such as immune function, psychological health, and depression. Few studies addressed the effects of different types of exercise interventions in older population samples with MCI. We will also be able to determine which type of exercise is more effective in the immune and hormonal function of this population.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 98 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Portugal 1 1%
Germany 1 1%
Unknown 96 98%

Demographic breakdown

Readers by professional status Count As %
Student > Master 18 18%
Student > Ph. D. Student 10 10%
Student > Bachelor 10 10%
Student > Doctoral Student 9 9%
Researcher 8 8%
Other 16 16%
Unknown 27 28%
Readers by discipline Count As %
Sports and Recreations 18 18%
Medicine and Dentistry 13 13%
Nursing and Health Professions 10 10%
Psychology 8 8%
Neuroscience 4 4%
Other 13 13%
Unknown 32 33%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 December 2018.
All research outputs
#16,999,224
of 25,760,414 outputs
Outputs from Frontiers in Public Health
#5,596
of 14,412 outputs
Outputs of similar age
#229,313
of 368,974 outputs
Outputs of similar age from Frontiers in Public Health
#49
of 68 outputs
Altmetric has tracked 25,760,414 research outputs across all sources so far. This one is in the 31st percentile – i.e., 31% of other outputs scored the same or lower than it.
So far Altmetric has tracked 14,412 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.6. This one has gotten more attention than average, scoring higher than 55% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 368,974 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 35th percentile – i.e., 35% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 68 others from the same source and published within six weeks on either side of this one. This one is in the 27th percentile – i.e., 27% of its contemporaries scored the same or lower than it.