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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Human Microphysiological Systems and Organoids as in Vitro Models for Toxicological Studies
|
|---|---|
| Published in |
Frontiers in Public Health, July 2018
|
| DOI | 10.3389/fpubh.2018.00185 |
| Pubmed ID | |
| Authors |
George A. Truskey |
| Abstract |
Organoids and microphysiological systems represent two current approaches to reproduce organ function in vitro. These systems can potentially provide unbiased assays of function which are needed to understand the mechanism of action of environmental toxins. Culture models that replicate organ function and interactions among cell types and tissues move beyond existing screens that target individual pathways and provide a means to assay context-dependent function. The current state of organoid cultures and microphysiological systems is reviewed and applications discussed. While few studies have examined environmental pollutants, studies with drugs demonstrate the power of these systems to assess toxicity as well as mechanism of action. Strengths and limitations of organoids and microphysiological systems are reviewed and challenges are identified to produce suitable high capacity functional assays. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Switzerland | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 94 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 94 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 18 | 19% |
| Student > Master | 14 | 15% |
| Researcher | 14 | 15% |
| Student > Bachelor | 8 | 9% |
| Student > Doctoral Student | 5 | 5% |
| Other | 5 | 5% |
| Unknown | 30 | 32% |
| Readers by discipline | Count | As % |
|---|---|---|
| Engineering | 12 | 13% |
| Biochemistry, Genetics and Molecular Biology | 12 | 13% |
| Pharmacology, Toxicology and Pharmaceutical Science | 9 | 10% |
| Agricultural and Biological Sciences | 7 | 7% |
| Chemical Engineering | 6 | 6% |
| Other | 15 | 16% |
| Unknown | 33 | 35% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 10 July 2018.
All research outputs
#18,641,800
of 23,094,276 outputs
Outputs from Frontiers in Public Health
#5,955
of 10,408 outputs
Outputs of similar age
#251,920
of 326,353 outputs
Outputs of similar age from Frontiers in Public Health
#65
of 74 outputs
Altmetric has tracked 23,094,276 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,408 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 10.0. This one is in the 25th percentile – i.e., 25% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 326,353 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 12th percentile – i.e., 12% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 74 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.