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Metamizole Utilization and Expenditure During 6-Year Period: Serbia vs. Croatia

Overview of attention for article published in Frontiers in Public Health, July 2018
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Title
Metamizole Utilization and Expenditure During 6-Year Period: Serbia vs. Croatia
Published in
Frontiers in Public Health, July 2018
DOI 10.3389/fpubh.2018.00213
Pubmed ID
Authors

Milijana Miljkovic, Viktorija Dragojevic-Simic, Nemanja Rancic, Radoje Simic, Tanja Pekez-Pavlisko, Aleksandra Kovacevic, Dusica Stamenkovic

Abstract

Background: Metamizole is a medication with analgesic, antipyretic, spasmolytic, and weak anti-inflammatory effects. The aim of our study was to evaluate a six-year trend in the utilization and expenditure of metamizole in comparison to other group of licensed non-opioid analgesics in Serbia and Croatia, in order to rationalize its use and prescribing in these countries. Methods: The data of metamizole vs. all other non-opioid analgesics utilization and expenditure in Serbia and Croatia was analyzed according to the WHO methodology and expressed as defined daily doses per 1,000 inhabitants per day (DDD/1,000 inhabitants/per day) and total costs, respectively, during the 6-year period from 2010 to 2015. Results: In the observed period, utilization of metamizole was 3.31 fold higher in Serbia than in Croatia (median in Serbia was 2.238 vs. 0.675 in Croatia DDD/1,000 inhabitants/per day/per year). Expenditure of metamizole in the same period was 5.29-fold higher in Serbia than in Croatia (median in Serbia was 1,738,192.51 €/per year vs. 328,355.03 €/per year in Croatia). Conclusion: Utilization and expenditure of non-opioid analgesics, including metamizole, in Serbia was significantly higher comparing with Croatia.Further research is needed to determine whether the current analgesic consumption in Serbia meets the needs of the patient. The benefits of metamizole should be weighed against the risk of metamizole-induced adverse effects. Until then, its prescribing should be based on indications and the appropriate duration of therapy.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 29 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 29 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 3 10%
Student > Bachelor 2 7%
Student > Master 2 7%
Student > Ph. D. Student 2 7%
Lecturer 1 3%
Other 3 10%
Unknown 16 55%
Readers by discipline Count As %
Pharmacology, Toxicology and Pharmaceutical Science 4 14%
Medicine and Dentistry 2 7%
Environmental Science 1 3%
Unspecified 1 3%
Arts and Humanities 1 3%
Other 4 14%
Unknown 16 55%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 26 July 2018.
All research outputs
#14,421,028
of 23,096,849 outputs
Outputs from Frontiers in Public Health
#3,688
of 10,418 outputs
Outputs of similar age
#186,312
of 330,319 outputs
Outputs of similar age from Frontiers in Public Health
#61
of 84 outputs
Altmetric has tracked 23,096,849 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 10,418 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 10.0. This one has gotten more attention than average, scoring higher than 61% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 330,319 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 40th percentile – i.e., 40% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 84 others from the same source and published within six weeks on either side of this one. This one is in the 22nd percentile – i.e., 22% of its contemporaries scored the same or lower than it.