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The Decade-Long Chinese Methadone Maintenance Therapy Yields Large Population and Economic Benefits for Drug Users in Reducing Harm, HIV and HCV Disease Burden

Overview of attention for article published in Frontiers in Public Health, November 2019
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Title
The Decade-Long Chinese Methadone Maintenance Therapy Yields Large Population and Economic Benefits for Drug Users in Reducing Harm, HIV and HCV Disease Burden
Published in
Frontiers in Public Health, November 2019
DOI 10.3389/fpubh.2019.00327
Pubmed ID
Authors

Lei Zhang, Xia Zou, Yong Xu, Nick Medland, Liwei Deng, Yin Liu, Shu Su, Li Ling

Abstract

Objectives: We aimed to conduct a comprehensive evaluation of the population impact of methadone maintenance treatment (MMT) for its future program planning. Methods: We conducted a literature review of the effects of MMT in China on HIV and HCV disease burden, injecting, and sexual behaviors and drug-related harm during 2004-2015. Data synthesis and analysis were conducted to obtain the pooled estimates of parameters for a mathematical model which was constructed to evaluate the effectiveness and cost-effectiveness of the program. Results: Based on a review of 134 articles, this study demonstrated that MMT is highly effective in reducing crime-related, high risk sexual, and injecting behaviors. The model estimated US$1,037 m which was invested in MMT from 2004 to 2015 has prevented 29,463 (15,325-43,600) new HIV infections, 130,563 (91,580-169,546) new HCV infections, 10,783 (10,380-11,187) deaths related to HIV, HCV and drug-related harm, and 338,920.0 (334,596.2-343,243.7) disability-adjusted life years (DALYs). The costs for each prevented HIV infection, HCV infection, death, and DALY were $35,206.8 (33,594.8-36,981.4), $7,944.7 ($7,714.4-8,189.2), $96,193.4 (92,726.0-99,930.2), and $3,060.6 ($3,022.0-3,100.1) respectively. Conclusion: The Chinese MMT program has been effective and cost-effective in reducing injecting, injecting-related risk behaviors and adversities due to HIV/HCV infection and drug-related harm among drug users.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 34 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 34 100%

Demographic breakdown

Readers by professional status Count As %
Student > Bachelor 6 18%
Student > Master 6 18%
Researcher 2 6%
Lecturer 1 3%
Lecturer > Senior Lecturer 1 3%
Other 3 9%
Unknown 15 44%
Readers by discipline Count As %
Medicine and Dentistry 5 15%
Nursing and Health Professions 4 12%
Immunology and Microbiology 2 6%
Engineering 2 6%
Social Sciences 2 6%
Other 2 6%
Unknown 17 50%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 November 2019.
All research outputs
#20,587,621
of 23,172,045 outputs
Outputs from Frontiers in Public Health
#7,885
of 10,569 outputs
Outputs of similar age
#305,632
of 359,983 outputs
Outputs of similar age from Frontiers in Public Health
#78
of 113 outputs
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So far Altmetric has tracked 10,569 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.9. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
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