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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Meningioma Genomics: Diagnostic, Prognostic, and Therapeutic Applications
|
|---|---|
| Published in |
Frontiers in Surgery, July 2016
|
| DOI | 10.3389/fsurg.2016.00040 |
| Pubmed ID | |
| Authors |
Wenya Linda Bi, Michael Zhang, Winona W. Wu, Yu Mei, Ian F. Dunn |
| Abstract |
There has been a recent revolution in our understanding of the genetic factors that drive meningioma, punctuating an equilibrium that has existed since Cushing's germinal studies nearly a century ago. A growing appreciation that meningiomas share similar biologic features with other malignancies has allowed extrapolation of management strategies and lessons from intra-axial central nervous system neoplasms and systemic cancers to meningiomas. These features include a natural proclivity for invasion, frequent intratumoral heterogeneity, and correlation between biologic profile and clinical behavior. Next-generation sequencing has characterized recurrent somatic mutations in NF2, TRAF7, KLF4, AKT1, SMO, and PIK3CA, which are collectively present in ~80% of sporadic meningiomas. Genomic features of meningioma further associate with tumor location, histologic subtype, and possibly clinical behavior. Such genomic decryption, along with advances in targeted pharmacotherapy, provides a maturing integrated view of meningiomas. We review recent advances in meningioma genomics and probe their potential applications in diagnostic, therapeutic, and prognostic frontiers. |
X Demographics
The data shown below were collected from the profiles of 6 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Montenegro | 1 | 17% |
| Switzerland | 1 | 17% |
| Unknown | 4 | 67% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 4 | 67% |
| Practitioners (doctors, other healthcare professionals) | 1 | 17% |
| Scientists | 1 | 17% |
Mendeley readers
The data shown below were compiled from readership statistics for 115 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 115 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 16 | 14% |
| Student > Ph. D. Student | 14 | 12% |
| Student > Postgraduate | 14 | 12% |
| Student > Doctoral Student | 10 | 9% |
| Student > Master | 9 | 8% |
| Other | 21 | 18% |
| Unknown | 31 | 27% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 48 | 42% |
| Neuroscience | 14 | 12% |
| Biochemistry, Genetics and Molecular Biology | 11 | 10% |
| Nursing and Health Professions | 3 | 3% |
| Agricultural and Biological Sciences | 2 | 2% |
| Other | 6 | 5% |
| Unknown | 31 | 27% |
Attention Score in Context
This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 August 2016.
All research outputs
#12,962,178
of 22,880,230 outputs
Outputs from Frontiers in Surgery
#311
of 2,896 outputs
Outputs of similar age
#180,559
of 355,479 outputs
Outputs of similar age from Frontiers in Surgery
#5
of 18 outputs
Altmetric has tracked 22,880,230 research outputs across all sources so far. This one is in the 42nd percentile – i.e., 42% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,896 research outputs from this source. They receive a mean Attention Score of 2.3. This one has done well, scoring higher than 88% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 355,479 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 48th percentile – i.e., 48% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 72% of its contemporaries.