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Fertility Preservation in Endometriosis Patients: Anti-Müllerian Hormone Is a Reliable Marker of the Ovarian Follicle Density

Overview of attention for article published in Frontiers in Surgery, July 2017
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  • Good Attention Score compared to outputs of the same age and source (66th percentile)

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Title
Fertility Preservation in Endometriosis Patients: Anti-Müllerian Hormone Is a Reliable Marker of the Ovarian Follicle Density
Published in
Frontiers in Surgery, July 2017
DOI 10.3389/fsurg.2017.00040
Pubmed ID
Authors

Elisabetta Garavaglia, Cinzia Sala, Gianluca Taccagni, Michela Traglia, Caterina Barbieri, Stefano Ferrari, Massimo Candiani, Paola Panina-Bordignon, Daniela Toniolo

Abstract

To analyze the ovarian reserve via measurement of follicular density and anti-Müllerian hormone (AMH) in endometriosis patients participating to a clinical program of cortical ovarian cryopreservation. Retrospective analysis of serum AMH levels and prospective investigation of ovarian follicle number. University Hospital. Two hundred and two women with endometriosis and 400 controls. Blood samples and ovarian biopsies. Correlation of serum AMH levels and the number of non-growing follicles in the biopsied cortical tissues in endometriosis and control subjects, including age, type of AMH kit, and the laboratory performing the analysis as covariates. AMH levels were shown to decrease with age in untreated endometriosis patients (P < 1.0 × 10(-5)) but they were significantly lower in endometriosis compared to controls only in patients over 36 years old (P = 2.7 × 10(-4)). The AMH decrease was faster in endometriosis compared to controls (beta = 0.27, P = 4.0 × 10(-4)). Primordial follicle number decreased with the reduction of AMH levels in both cases and controls (beta = 0.3; P = 0.04). AMH is a reliable marker of ovarian reserve in endometriosis patients, and it can predict follicular density in women undergoing ovarian tissue cryopreservation.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 39 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 39 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 7 18%
Researcher 5 13%
Student > Doctoral Student 4 10%
Student > Bachelor 4 10%
Lecturer 3 8%
Other 5 13%
Unknown 11 28%
Readers by discipline Count As %
Medicine and Dentistry 15 38%
Biochemistry, Genetics and Molecular Biology 3 8%
Agricultural and Biological Sciences 2 5%
Engineering 2 5%
Computer Science 1 3%
Other 2 5%
Unknown 14 36%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 12 September 2017.
All research outputs
#17,906,525
of 22,990,068 outputs
Outputs from Frontiers in Surgery
#781
of 2,965 outputs
Outputs of similar age
#227,619
of 316,990 outputs
Outputs of similar age from Frontiers in Surgery
#6
of 18 outputs
Altmetric has tracked 22,990,068 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,965 research outputs from this source. They receive a mean Attention Score of 2.3. This one has gotten more attention than average, scoring higher than 68% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 316,990 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 23rd percentile – i.e., 23% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 18 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 66% of its contemporaries.