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Chromium Propionate Enhances Adipogenic Differentiation of Bovine Intramuscular Adipocytes

Overview of attention for article published in Frontiers in Veterinary Science, September 2015
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Title
Chromium Propionate Enhances Adipogenic Differentiation of Bovine Intramuscular Adipocytes
Published in
Frontiers in Veterinary Science, September 2015
DOI 10.3389/fvets.2015.00026
Pubmed ID
Authors

Rebecca J. Tokach, Flavio R. B. Ribeiro, Ki Yong Chung, Whitney Rounds, Bradley J. Johnson

Abstract

In vitro experiments were performed to determine the effects of increasing concentrations of chromium propionate (CrPro) on mRNA and protein abundance of different enzymes and receptors. Intramuscular (IM) and subcutaneous (SC) preadipocytes and bovine satellite cells were isolated from the longissimus muscle to determine the effect of treatment on glucose transporter type 4 (GLUT4) and peroxisome proliferator-activated receptor γ mRNA and GLUT4 protein abundance. Preadipocyte cultures were treated with differentiation media plus either sodium propionate or different concentrations of CrPro for 96, 120, and 144 h before harvest. This study indicated that adipogenesis of the bovine IM adipocytes were more sensitive to the treatment of CrPro as compared to SC adipocytes. Enhancement of adenosine monophosphate-activated protein kinase and GLUT4 mRNA by CrPro treatment may enhance glucose uptake in IM adipocytes. CrPro decreased GLUT4 protein levels in muscle cell cultures suggesting that those cells have increased efficiency of glucose uptake due to exposure to increased levels of CrPro. In contrast, each of the two adipogenic lines had opposing responses to the CrPro. It appeared that CrPro had the most stimulative effect of GLUT4 response in the IM adipocytes as compared to SC adipocytes. These findings indicated opportunities to potentially augment marbling in beef cattle fed CrPro during the finishing phase.

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The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Argentina 1 8%
Unknown 11 92%

Demographic breakdown

Readers by professional status Count As %
Other 2 17%
Student > Bachelor 2 17%
Unspecified 1 8%
Student > Doctoral Student 1 8%
Student > Ph. D. Student 1 8%
Other 2 17%
Unknown 3 25%
Readers by discipline Count As %
Agricultural and Biological Sciences 4 33%
Medicine and Dentistry 2 17%
Unspecified 1 8%
Unknown 5 42%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 December 2015.
All research outputs
#14,236,953
of 22,826,360 outputs
Outputs from Frontiers in Veterinary Science
#2,296
of 6,200 outputs
Outputs of similar age
#138,286
of 267,498 outputs
Outputs of similar age from Frontiers in Veterinary Science
#11
of 27 outputs
Altmetric has tracked 22,826,360 research outputs across all sources so far. This one is in the 35th percentile – i.e., 35% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,200 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one has gotten more attention than average, scoring higher than 57% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 267,498 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 45th percentile – i.e., 45% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 27 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 51% of its contemporaries.