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MicroRNAs in the Host Response to Viral Infections of Veterinary Importance

Overview of attention for article published in Frontiers in Veterinary Science, October 2016
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Title
MicroRNAs in the Host Response to Viral Infections of Veterinary Importance
Published in
Frontiers in Veterinary Science, October 2016
DOI 10.3389/fvets.2016.00086
Pubmed ID
Authors

Mohamed Samir, Lea A. I. Vaas, Frank Pessler

Abstract

The discovery of small regulatory non-coding RNAs has been an exciting advance in the field of genomics. MicroRNAs (miRNAs) are endogenous RNA molecules, approximately 22 nucleotides in length, that regulate gene expression, mostly at the posttranscriptional level. MiRNA profiling technologies have made it possible to identify and quantify novel miRNAs and to study their regulation and potential roles in disease pathogenesis. Although miRNAs have been extensively investigated in viral infections of humans, their implications in viral diseases affecting animals of veterinary importance are much less understood. The number of annotated miRNAs in different animal species is growing continuously, and novel roles in regulating host-pathogen interactions are being discovered, for instance, miRNA-mediated augmentation of viral transcription and replication. In this review, we present an overview of synthesis and function of miRNAs and an update on the current state of research on host-encoded miRNAs in the genesis of viral infectious diseases in their natural animal host as well as in selected in vivo and in vitro laboratory models.

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The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 52 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 13 25%
Student > Master 7 13%
Student > Ph. D. Student 7 13%
Student > Doctoral Student 5 10%
Student > Bachelor 4 8%
Other 7 13%
Unknown 9 17%
Readers by discipline Count As %
Agricultural and Biological Sciences 11 21%
Biochemistry, Genetics and Molecular Biology 10 19%
Veterinary Science and Veterinary Medicine 6 12%
Immunology and Microbiology 4 8%
Psychology 2 4%
Other 8 15%
Unknown 11 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 17 November 2016.
All research outputs
#18,475,157
of 22,893,031 outputs
Outputs from Frontiers in Veterinary Science
#4,147
of 6,278 outputs
Outputs of similar age
#238,712
of 315,552 outputs
Outputs of similar age from Frontiers in Veterinary Science
#28
of 35 outputs
Altmetric has tracked 22,893,031 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,278 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 315,552 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 35 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.