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Challenges of Generating and Maintaining Protective Vaccine-Induced Immune Responses for Foot-and-Mouth Disease Virus in Pigs

Overview of attention for article published in Frontiers in Veterinary Science, November 2016
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  • Above-average Attention Score compared to outputs of the same age and source (56th percentile)

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Title
Challenges of Generating and Maintaining Protective Vaccine-Induced Immune Responses for Foot-and-Mouth Disease Virus in Pigs
Published in
Frontiers in Veterinary Science, November 2016
DOI 10.3389/fvets.2016.00102
Pubmed ID
Authors

Nicholas A. Lyons, Young S. Lyoo, Donald P. King, David J. Paton

Abstract

Vaccination can play a central role in the control of outbreaks of foot-and-mouth disease (FMD) by reducing both the impact of clinical disease and the extent of virus transmission between susceptible animals. Recent incursions of exotic FMD virus lineages into several East Asian countries have highlighted the difficulties of generating and maintaining an adequate immune response in vaccinated pigs. Factors that impact vaccine performance include (i) the potency, antigenic payload, and formulation of a vaccine; (ii) the antigenic match between the vaccine and the heterologous circulating field strain; and (iii) the regime (timing, frequency, and herd-level coverage) used to administer the vaccine. This review collates data from studies that have evaluated the performance of foot-and-mouth disease virus vaccines at the individual and population level in pigs and identifies research priorities that could provide new insights to improve vaccination in the future.

X Demographics

X Demographics

The data shown below were collected from the profiles of 3 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 50 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 50 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 14 28%
Student > Ph. D. Student 7 14%
Student > Doctoral Student 4 8%
Student > Master 4 8%
Other 3 6%
Other 5 10%
Unknown 13 26%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 12 24%
Agricultural and Biological Sciences 8 16%
Biochemistry, Genetics and Molecular Biology 4 8%
Immunology and Microbiology 3 6%
Medicine and Dentistry 3 6%
Other 3 6%
Unknown 17 34%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 01 December 2016.
All research outputs
#13,998,251
of 22,903,988 outputs
Outputs from Frontiers in Veterinary Science
#2,087
of 6,283 outputs
Outputs of similar age
#218,186
of 415,970 outputs
Outputs of similar age from Frontiers in Veterinary Science
#14
of 32 outputs
Altmetric has tracked 22,903,988 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 6,283 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.9. This one has gotten more attention than average, scoring higher than 63% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 415,970 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 46th percentile – i.e., 46% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 32 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 56% of its contemporaries.