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Gene Therapy Using Plasmid DNA Encoding Vascular Endothelial Growth Factor 164 and Fibroblast Growth Factor 2 Genes for the Treatment of Horse Tendinitis and Desmitis: Case Reports

Overview of attention for article published in Frontiers in Veterinary Science, October 2017
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (98th percentile)

Mentioned by

news
13 news outlets
blogs
2 blogs
twitter
13 X users
facebook
3 Facebook pages

Citations

dimensions_citation
22 Dimensions

Readers on

mendeley
49 Mendeley
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Title
Gene Therapy Using Plasmid DNA Encoding Vascular Endothelial Growth Factor 164 and Fibroblast Growth Factor 2 Genes for the Treatment of Horse Tendinitis and Desmitis: Case Reports
Published in
Frontiers in Veterinary Science, October 2017
DOI 10.3389/fvets.2017.00168
Pubmed ID
Authors

Milomir Kovac, Yaroslav A. Litvin, Ruslan O. Aliev, Elena Yu Zakirova, Catrin S. Rutland, Andrey P. Kiyasov, Albert A. Rizvanov

Abstract

In this clinical study, for the first time we used the direct gene therapy to restore severe injuries of the suspensory ligament branch and superficial digital flexor tendon in horses (Equus caballus). We injected the plasmid DNA encoding two therapeutic species-specific growth factors: vascular endothelial growth factor 164 and fibroblast growth factor 2 at the site of injury in the suspensory ligament branch and tendon. Treatment effects were evaluated with the use of clinical observation and ultrasound imaging during a period of a few months. We showed that gene therapy used within a period of 2-3 months after the injury resulted in the complete recovery of functions and full restoration of the severely damaged suspensory ligament and superficial digital flexor tendon.

X Demographics

X Demographics

The data shown below were collected from the profiles of 13 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 49 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 11 22%
Student > Bachelor 6 12%
Student > Master 6 12%
Professor 4 8%
Other 4 8%
Other 6 12%
Unknown 12 24%
Readers by discipline Count As %
Veterinary Science and Veterinary Medicine 11 22%
Agricultural and Biological Sciences 8 16%
Biochemistry, Genetics and Molecular Biology 4 8%
Medicine and Dentistry 4 8%
Economics, Econometrics and Finance 2 4%
Other 6 12%
Unknown 14 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 118. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 September 2018.
All research outputs
#341,188
of 24,811,594 outputs
Outputs from Frontiers in Veterinary Science
#82
of 7,626 outputs
Outputs of similar age
#7,294
of 329,734 outputs
Outputs of similar age from Frontiers in Veterinary Science
#2
of 60 outputs
Altmetric has tracked 24,811,594 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 7,626 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 7.1. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 329,734 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 60 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 98% of its contemporaries.