Title |
Myositis, Ganglioneuritis, and Myocarditis with Distinct Perifascicular Muscle Atrophy in a 2-Year-Old Male Boxer
|
---|---|
Published in |
Frontiers in Veterinary Science, February 2018
|
DOI | 10.3389/fvets.2018.00020 |
Pubmed ID | |
Authors |
Paul M. Rossman, Stephanie A. Thomovsky, Ryan M. Schafbuch, Ling T. Guo, G. D. Shelton |
Abstract |
A 2-year-old male, intact Boxer was referred for chronic diarrhea, hyporexia, labored breathing, weakness and elevated creatine kinase, and alanine aminotransferase activities. Initial examination and diagnostics revealed a peripheral nervous system neurolocalization, atrial premature complexes, and generalized megaesophagus. Progressive worsening of the dog's condition was noted after 36 h; the dog developed aspiration pneumonia, was febrile and oxygen dependent. The owners elected humane euthanasia. Immediately postmortem biopsies of the left cranial tibial and triceps muscles and the left peroneal nerve were obtained. Postmortem histology revealed concurrent myositis, myocarditis, endocarditis, and ganglioneuritis. Mixed mononuclear cell infiltrations and a distinct perifascicular pattern of muscle fiber atrophy was present in both muscles. This is a novel case of diffuse inflammatory myopathy with a distinct perifascicular pattern of atrophy in addition to endocarditis, myocarditis, and epicarditis. |
X Demographics
Geographical breakdown
Country | Count | As % |
---|---|---|
Switzerland | 1 | 50% |
Unknown | 1 | 50% |
Demographic breakdown
Type | Count | As % |
---|---|---|
Members of the public | 2 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
---|---|---|
Unknown | 31 | 100% |
Demographic breakdown
Readers by professional status | Count | As % |
---|---|---|
Other | 7 | 23% |
Unspecified | 3 | 10% |
Student > Postgraduate | 3 | 10% |
Researcher | 3 | 10% |
Student > Bachelor | 3 | 10% |
Other | 6 | 19% |
Unknown | 6 | 19% |
Readers by discipline | Count | As % |
---|---|---|
Veterinary Science and Veterinary Medicine | 16 | 52% |
Unspecified | 3 | 10% |
Medicine and Dentistry | 3 | 10% |
Nursing and Health Professions | 1 | 3% |
Sports and Recreations | 1 | 3% |
Other | 1 | 3% |
Unknown | 6 | 19% |