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Mendeley readers
Attention Score in Context
| Title |
Double Trouble? Potential for Hyperexcitability Following Both Channelopathic up- and Downregulation of Ih in Epilepsy
|
|---|---|
| Published in |
Frontiers in Neuroscience, May 2009
|
| DOI | 10.3389/neuro.01.005.2009 |
| Pubmed ID | |
| Authors |
Jonas Dyhrfjeld-Johnsen, Robert J. Morgan, Ivan Soltesz |
| Abstract |
Studies of pathological ion channel regulation as an underlying mechanism of epilepsy have revealed alterations in the h-current in several animal models. While earlier reports indicate that downregulation of the h-current is pro-excitatory on the single neuron level, we found an upregulation of I(h) in hyperexcitable CA1 pyramidal neuron dendrites following experimental febrile seizures. In addition, in several CA1 pyramidal neuron computational models of different complexity, h-current upregulation has been shown to lead to pro-excitable effects. This focused review examines the complex impact of altered h-current on neuronal resting membrane potential (RMP) and input resistance (R(in)), as well as reported interactions with other ionic conductances. |
Mendeley readers
The data shown below were compiled from readership statistics for 81 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 3 | 4% |
| India | 2 | 2% |
| France | 1 | 1% |
| Germany | 1 | 1% |
| United States | 1 | 1% |
| Unknown | 73 | 90% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Researcher | 20 | 25% |
| Student > Ph. D. Student | 16 | 20% |
| Student > Master | 11 | 14% |
| Professor | 5 | 6% |
| Professor > Associate Professor | 5 | 6% |
| Other | 13 | 16% |
| Unknown | 11 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 37 | 46% |
| Neuroscience | 16 | 20% |
| Medicine and Dentistry | 6 | 7% |
| Engineering | 2 | 2% |
| Psychology | 2 | 2% |
| Other | 3 | 4% |
| Unknown | 15 | 19% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 23 September 2009.
All research outputs
#17,285,036
of 25,371,288 outputs
Outputs from Frontiers in Neuroscience
#8,065
of 11,538 outputs
Outputs of similar age
#88,602
of 104,030 outputs
Outputs of similar age from Frontiers in Neuroscience
#6
of 7 outputs
Altmetric has tracked 25,371,288 research outputs across all sources so far. This one is in the 21st percentile – i.e., 21% of other outputs scored the same or lower than it.
So far Altmetric has tracked 11,538 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.9. This one is in the 24th percentile – i.e., 24% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 104,030 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 7 others from the same source and published within six weeks on either side of this one.