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X Demographics
Mendeley readers
Attention Score in Context
| Title |
The Impact of Dietary Energy Intake on Cognitive Aging
|
|---|---|
| Published in |
Frontiers in Aging Neuroscience, January 2010
|
| DOI | 10.3389/neuro.24.005.2010 |
| Pubmed ID | |
| Authors |
Mark P. Mattson |
| Abstract |
Rodents that are insulin resistant and obese as the result of genetic factors, overeating and/or a sedentary lifestyle, exhibit cognitive deficits that worsen with advancing age compared to their more svelte counterparts. Data from epidemiological and clinical studies suggest similar adverse effects of excessive dietary energy intake and insulin resistance on cognition in humans. Our findings from studies of animal models suggest that dietary energy restriction can enhance neural plasticity and reduce the vulnerability of the brain to age-related dysfunction and disease. Dietary energy restriction may exert beneficial effects on the brain by engaging adaptive cellular stress response pathways resulting in the up-regulation of genes that encode proteins that promote neural plasticity and cell survival (e.g., neurotrophic factors, protein chaperones and redox enzymes). Two energy state-sensitive factors that are proving particularly important in regulating energy balance and improving/preserving cognitive function are brain-derived neurotrophic factor and glucagon-like peptide 1. Alternate day calorie restriction, novel insulin-sensitizing and neuroprotective agents, and drugs that activate adaptive stress response pathways, are examples of approaches for preserving cognitive function that show promise in preclinical studies. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United Kingdom | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 159 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 2 | 1% |
| Germany | 1 | <1% |
| India | 1 | <1% |
| Indonesia | 1 | <1% |
| Japan | 1 | <1% |
| United Kingdom | 1 | <1% |
| Unknown | 152 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 32 | 20% |
| Student > Master | 26 | 16% |
| Researcher | 23 | 14% |
| Student > Bachelor | 15 | 9% |
| Student > Doctoral Student | 11 | 7% |
| Other | 26 | 16% |
| Unknown | 26 | 16% |
| Readers by discipline | Count | As % |
|---|---|---|
| Agricultural and Biological Sciences | 37 | 23% |
| Medicine and Dentistry | 27 | 17% |
| Neuroscience | 17 | 11% |
| Psychology | 15 | 9% |
| Nursing and Health Professions | 10 | 6% |
| Other | 21 | 13% |
| Unknown | 32 | 20% |
Attention Score in Context
This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 25 June 2013.
All research outputs
#17,690,153
of 22,712,476 outputs
Outputs from Frontiers in Aging Neuroscience
#3,770
of 4,732 outputs
Outputs of similar age
#149,267
of 163,643 outputs
Outputs of similar age from Frontiers in Aging Neuroscience
#25
of 29 outputs
Altmetric has tracked 22,712,476 research outputs across all sources so far. This one is in the 19th percentile – i.e., 19% of other outputs scored the same or lower than it.
So far Altmetric has tracked 4,732 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 13.1. This one is in the 15th percentile – i.e., 15% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 163,643 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 8th percentile – i.e., 8% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 29 others from the same source and published within six weeks on either side of this one. This one is in the 13th percentile – i.e., 13% of its contemporaries scored the same or lower than it.