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The Relationship between the Blood Level of Persistent Organic Pollutants and Common Gastrointestinal Symptoms

Overview of attention for article published in Korean Journal of Family Medicine, July 2017
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Title
The Relationship between the Blood Level of Persistent Organic Pollutants and Common Gastrointestinal Symptoms
Published in
Korean Journal of Family Medicine, July 2017
DOI 10.4082/kjfm.2017.38.4.233
Pubmed ID
Authors

Hyo-Min Kim, Chang-Ho Youn, Hae Jin Ko, Seon-Hwa Lee, Yu-Mi Lee

Abstract

Persistent organic pollutants (POPs) are toxic materials that cannot be broken down naturally and that easily accumulate in the body. Although several studies have attempted to uncover the effects of POPs on the endocrine and nervous systems and on cancer, few focus on the relationship between low-dose POPs and public health. Here, we attempt to determine the relationship between the level of POPs and common gastrointestinal symptoms, including abdominal discomfort, diarrhea, and constipation. We recruited 121 subjects who visited Kyungpook National University Medical Center for health screening. Plasma concentrations were evaluated for 40 kinds of POPs including 17 types of polychlorinated biphenyls (PCBs) and 23 types of organochlorine pesticides (OCP). Furthermore, the Korean version of the Rome III criteria was used to identify gastrointestinal symptoms. Based on our results, abdominal discomfort showed an inverse relationship with several PCBs and an inverted U-shaped relationship with several other OCPs including pp-DDD and pp-DDT. The effects of pp-DDD and pp-DDT on abdominal discomfort were similar to those of OCPs on obesity and metabolic syndrome. Our results suggest that mild and unspecified gastrointestinal symptoms with no clear causes could be related to POP levels.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 16 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 16 100%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 3 19%
Student > Bachelor 2 13%
Professor 1 6%
Student > Master 1 6%
Researcher 1 6%
Other 1 6%
Unknown 7 44%
Readers by discipline Count As %
Medicine and Dentistry 2 13%
Biochemistry, Genetics and Molecular Biology 1 6%
Psychology 1 6%
Agricultural and Biological Sciences 1 6%
Neuroscience 1 6%
Other 1 6%
Unknown 9 56%