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Mendeley readers
| Title |
Evaluation of the neurological safety of epidurally-administered pregabalin in rats
|
|---|---|
| Published in |
Korean Journal of Anesthesiology, January 2012
|
| DOI | 10.4097/kjae.2012.62.1.57 |
| Pubmed ID | |
| Authors |
Jeong Rim Lee, Pyung-Bok Lee, Gheeyoung Choe, Sang Chul Lee, Hyo Min Lee, Eunjung Kim, Yong Chul Kim |
| Abstract |
The primary site of action of pregabalin, i.e. the α-2-δ subunit of the voltage-dependent calcium channel, is located at the dorsal root ganglion and dorsal horn of the spinal cord. Therefore, the epidural administration of pregabalin could have advantages over oral administration. However, the possibility of its neurotoxicity should be excluded before any attempt at epidural administration. We evaluated the neuronal safety of epidurally-administered pregabalin by observing the sensory/motor changes and examining the histopathology of spinal cord in rats. |
Mendeley readers
The data shown below were compiled from readership statistics for 14 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 14 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 3 | 21% |
| Student > Bachelor | 3 | 21% |
| Researcher | 2 | 14% |
| Student > Doctoral Student | 1 | 7% |
| Student > Master | 1 | 7% |
| Other | 1 | 7% |
| Unknown | 3 | 21% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 5 | 36% |
| Nursing and Health Professions | 2 | 14% |
| Agricultural and Biological Sciences | 2 | 14% |
| Pharmacology, Toxicology and Pharmaceutical Science | 1 | 7% |
| Chemistry | 1 | 7% |
| Other | 0 | 0% |
| Unknown | 3 | 21% |