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Mendeley readers
| Title |
Parthenolide Sensitizes Human Colorectal Cancer Cells to Tumor Necrosis Factor-related Apoptosis-inducing Ligand through Mitochondrial and Caspase Dependent Pathway
|
|---|---|
| Published in |
Intestinal Research , January 2014
|
| DOI | 10.5217/ir.2014.12.1.34 |
| Pubmed ID | |
| Authors |
Kieu Thi Thu Trang, Se-Lim Kim, Sang-Bae Park, Seung-Young Seo, Chung-Hwan Choi, Jin-Kyoung Park, Jin-Chang Moon, Soo-Teik Lee, Sang-Wook Kim |
| Abstract |
Combination therapy utilizing tumor necrosis factor (TNF)-related apoptosis-inducing ligand (TRAIL) in conjunction with other anticancer agents, is a promising strategy to overcome TRAIL resistance in malignant cells. Recently, parthenolide (PT) has proved to be a promising anticancer agent, and several studies have explored its use in combination therapy. Here, we investigated the molecular mechanisms by which PT sensitizes colorectal cancer (CRC) cells to TRAIL-induced apoptosis. |
Mendeley readers
The data shown below were compiled from readership statistics for 12 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 12 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Bachelor | 3 | 25% |
| Student > Ph. D. Student | 2 | 17% |
| Student > Master | 2 | 17% |
| Student > Doctoral Student | 2 | 17% |
| Unspecified | 1 | 8% |
| Other | 0 | 0% |
| Unknown | 2 | 17% |
| Readers by discipline | Count | As % |
|---|---|---|
| Pharmacology, Toxicology and Pharmaceutical Science | 3 | 25% |
| Agricultural and Biological Sciences | 2 | 17% |
| Medicine and Dentistry | 2 | 17% |
| Nursing and Health Professions | 1 | 8% |
| Unspecified | 1 | 8% |
| Other | 1 | 8% |
| Unknown | 2 | 17% |