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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Detection of fecal shedding of rotavirus vaccine in infants following their first dose of pentavalent rotavirus vaccine
|
|---|---|
| Published in |
Vaccine, April 2011
|
| DOI | 10.1016/j.vaccine.2011.03.074 |
| Pubmed ID | |
| Authors |
Catherine Yen, Kathleen Jakob, Mathew D. Esona, Ximara Peckham, John Rausch, Jennifer J. Hull, Susan Whittier, Jon R. Gentsch, Philip LaRussa |
| Abstract |
Studies on rotavirus vaccine shedding and its potential transmission within households including immunocompromised individuals are needed to better define the potential risks and benefits of vaccination. We examined fecal shedding of pentavalent rotavirus vaccine (RV5) for 9 days following the first dose of vaccine in infants between 6 and 12 weeks of age. Rotavirus antigen was detected by enzyme immunoassay (EIA), and vaccine-type rotavirus was identified by nucleotide sequencing based on genetic relatedness to the RV5 VP6 gene. Stool from 22 (21.4%) of 103 children contained rotavirus antigen-positive specimens on ≥ 1 post-vaccination days. Rotavirus antigen was detected as early as post-vaccination day 3 and as late as day 9, with peak numbers of shedding on post-vaccination days 6 through 8. Vaccine-type rotavirus was detected in all 50 antigen-positive specimens and 8 of 8 antigen-negative specimens. Nine (75%) of 12 EIA-positive and 1 EIA-negative samples tested culture-positive for vaccine-type rotavirus. Fecal shedding of rotavirus vaccine virus after the first dose of RV5 occurred over a wide range of post-vaccination days not previously studied. These findings will help better define the potential for horizontal transmission of vaccine virus among immunocompromised household contacts of vaccinated infants for future studies. |
X Demographics
The data shown below were collected from the profiles of 30 X users who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 8 | 27% |
| United Kingdom | 3 | 10% |
| Denmark | 1 | 3% |
| Canada | 1 | 3% |
| Unknown | 17 | 57% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Members of the public | 25 | 83% |
| Practitioners (doctors, other healthcare professionals) | 3 | 10% |
| Scientists | 1 | 3% |
| Science communicators (journalists, bloggers, editors) | 1 | 3% |
Mendeley readers
The data shown below were compiled from readership statistics for 49 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| France | 1 | 2% |
| South Africa | 1 | 2% |
| Unknown | 47 | 96% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Student > Ph. D. Student | 10 | 20% |
| Student > Bachelor | 8 | 16% |
| Researcher | 6 | 12% |
| Student > Master | 6 | 12% |
| Other | 5 | 10% |
| Other | 7 | 14% |
| Unknown | 7 | 14% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 20 | 41% |
| Agricultural and Biological Sciences | 8 | 16% |
| Immunology and Microbiology | 3 | 6% |
| Pharmacology, Toxicology and Pharmaceutical Science | 2 | 4% |
| Nursing and Health Professions | 2 | 4% |
| Other | 5 | 10% |
| Unknown | 9 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 145. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 December 2023.
All research outputs
#284,870
of 25,373,627 outputs
Outputs from Vaccine
#274
of 16,509 outputs
Outputs of similar age
#898
of 120,531 outputs
Outputs of similar age from Vaccine
#1
of 176 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 98th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 16,509 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 17.7. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 120,531 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 99% of its contemporaries.
We're also able to compare this research output to 176 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 99% of its contemporaries.