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Prevalence of insulin resistance and metabolic syndrome in patients with gouty arthritis

Overview of attention for article published in Rheumatology International, December 2009
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  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#48 of 2,517)
  • High Attention Score compared to outputs of the same age (97th percentile)
  • High Attention Score compared to outputs of the same age and source (95th percentile)

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54 X users

Citations

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Title
Prevalence of insulin resistance and metabolic syndrome in patients with gouty arthritis
Published in
Rheumatology International, December 2009
DOI 10.1007/s00296-009-1304-x
Pubmed ID
Authors

Han-Gyul Yoo, Sang-Il Lee, Han-Jung Chae, Seoung Ju Park, Yong Chul Lee, Wan-Hee Yoo

Abstract

The study was performed to confirm the high prevalence of metabolic syndrome in gouty patients and to define the relationship between insulin resistance and gouty arthritis. We recruited 83 patients with gouty arthritis and checked clinical factors according to the diagnostic criteria of metabolic syndrome from the ATP III guidelines and WHO Asia-Pacific obesity criteria recommendations. We also assessed the clinical characteristics of subjects and homeostasis model assessment of insulin resistance (HOMA-IR) and compared with previous study groups as controls. The prevalence of metabolic syndrome in patients with gout was 30.1% according to ATP III criteria and 50.6% with WHO Asia-Pacific adjustment and is significantly higher than the previous control study groups (ATP III: 5.2, 10.6%, WHO Asia-Pacific adjustment: 9.8, 13.9%). The mean value of HOMA-IR in patients with gout was 2.63 ± 1.36 and is significantly higher than control study (1.91 ± 1.01, P < 0.05). There were significant correlations between 24-h urinary uric acid excretion and waist circumference (r(2) = 0.225, P = 0.049), fasting insulin (r(2) = 0.241, P = 0.035), and insulin resistance (HOMA-IR) (r(2) = 0.271, P = 0.017). There were significant correlations between insulin resistance and waist circumference (r(2) = 0.341, P < 0.01), BMI (r(2) = 0.390, P < 0.01). The value of HOMA-IR (insulin resistance) and the prevalence of metabolic syndrome in patients with gout are significantly higher than normal healthy control groups. The hyperuricemia in gout might be caused by the increased adiposity associated with insulin resistance.

X Demographics

X Demographics

The data shown below were collected from the profiles of 54 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 33 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 33 100%

Demographic breakdown

Readers by professional status Count As %
Researcher 6 18%
Other 4 12%
Student > Bachelor 3 9%
Student > Postgraduate 3 9%
Student > Ph. D. Student 3 9%
Other 6 18%
Unknown 8 24%
Readers by discipline Count As %
Medicine and Dentistry 15 45%
Biochemistry, Genetics and Molecular Biology 3 9%
Pharmacology, Toxicology and Pharmaceutical Science 1 3%
Chemical Engineering 1 3%
Nursing and Health Professions 1 3%
Other 3 9%
Unknown 9 27%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 36. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 13 November 2023.
All research outputs
#1,144,271
of 25,774,185 outputs
Outputs from Rheumatology International
#48
of 2,517 outputs
Outputs of similar age
#4,396
of 174,213 outputs
Outputs of similar age from Rheumatology International
#1
of 20 outputs
Altmetric has tracked 25,774,185 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,517 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 6.0. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 174,213 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 97% of its contemporaries.
We're also able to compare this research output to 20 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 95% of its contemporaries.