Structure of the voltage-gated calcium channel Cav1.1 at 3.6 Å resolution

Overview of attention for article published in Nature, August 2016

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近原子级分辨率的真核钙离子通道(Nature)

Nature Asia , 07 Sep 2016

电压门控钙离子通道能将膜电信号转化成细胞内的Ca 2+ 调节事件。例如，Ca V 1.1只在骨骼肌中表达，并且充当兴奋-收缩偶联的电压传感器。作者报告了兔源Ca v 1.1的3.6埃分辨率冷冻电镜结构。核心α1亚基的高分辨率使详细检测离子渗透路径成为可能，结…

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