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Hair toxic and essential trace elements in children with autism spectrum disorder

Overview of attention for article published in Metabolic Brain Disease, August 2016
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  • In the top 25% of all research outputs scored by Altmetric
  • Good Attention Score compared to outputs of the same age (73rd percentile)
  • Good Attention Score compared to outputs of the same age and source (79th percentile)

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Title
Hair toxic and essential trace elements in children with autism spectrum disorder
Published in
Metabolic Brain Disease, August 2016
DOI 10.1007/s11011-016-9899-6
Pubmed ID
Authors

Anatoly V. Skalny, Natalia V. Simashkova, Tatiana P. Klyushnik, Andrei R. Grabeklis, Geir Bjørklund, Margarita G. Skalnaya, Alexandr A. Nikonorov, Alexey A. Tinkov

Abstract

The objective of the study was to investigate hair trace elements content in children suffering from autism spectrum disorder (ASD). A total of 74 ASD children and 74 sex- and age-matched controls divided into two age groups (2-4 and 5-9 years) were investigated. Hair trace elements content was assessed using inductively coupled plasma mass spectrometry. A general cohort of ASD children was characterized by 29 %, 41 %, and 24 % lower hair levels of chromium (Cr), iodine (I), and vanadium (V), respectively, whereas the level of selenium (Se) exceeded the respective control values by 31 %. In ASD children aged 2-4 years hair Cr, I and V content was 68 %, 36 % and 41 % lower than in the controls. Older ASD children were characterized by 45 % increase in hair Se levels. In a general cohort of ASD children hair beryllium (Be) and tin (Sn) levels were 50 % and 34 % lower than the control values. In the first age group (2-4 years) of ASD children 34 %, 42 %, and 73 % lower levels of arsenic (As), boron (B), and Be were detected. In the second age group of ASD children only a nearly significant 25 % decrease in hair lead (Pb) was detected. Surprisingly, no significant group difference in hair mercury (Hg), zinc (Zn), and copper (Cu) content was detected. Generally, the results of the present study demonstrate that children with ASD are characterized by lower values in hair of not only essential but also toxic trace elements.

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X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 86 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Spain 1 1%
Unknown 85 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 10 12%
Researcher 9 10%
Student > Bachelor 9 10%
Student > Master 8 9%
Other 5 6%
Other 15 17%
Unknown 30 35%
Readers by discipline Count As %
Biochemistry, Genetics and Molecular Biology 11 13%
Medicine and Dentistry 11 13%
Psychology 7 8%
Agricultural and Biological Sciences 4 5%
Environmental Science 4 5%
Other 16 19%
Unknown 33 38%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 6. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 11 March 2018.
All research outputs
#6,304,362
of 25,654,806 outputs
Outputs from Metabolic Brain Disease
#316
of 1,184 outputs
Outputs of similar age
#91,367
of 349,332 outputs
Outputs of similar age from Metabolic Brain Disease
#5
of 24 outputs
Altmetric has tracked 25,654,806 research outputs across all sources so far. Compared to these this one has done well and is in the 75th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 1,184 research outputs from this source. They typically receive a little more attention than average, with a mean Attention Score of 5.7. This one has gotten more attention than average, scoring higher than 73% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 349,332 tracked outputs that were published within six weeks on either side of this one in any source. This one has gotten more attention than average, scoring higher than 73% of its contemporaries.
We're also able to compare this research output to 24 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 79% of its contemporaries.