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DNA Methylation as an Adjunct to Histopathology to Detect Prevalent, Inconspicuous Dysplasia and Early-Stage Neoplasia in Barrett's Esophagus

Overview of attention for article published in Clinical Cancer Research, February 2013
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About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • High Attention Score compared to outputs of the same age (88th percentile)
  • High Attention Score compared to outputs of the same age and source (85th percentile)

Mentioned by

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2 X users
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4 patents

Citations

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66 Dimensions

Readers on

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70 Mendeley
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Title
DNA Methylation as an Adjunct to Histopathology to Detect Prevalent, Inconspicuous Dysplasia and Early-Stage Neoplasia in Barrett's Esophagus
Published in
Clinical Cancer Research, February 2013
DOI 10.1158/1078-0432.ccr-12-2880
Pubmed ID
Authors

Muhammad A. Alvi, Xinxue Liu, Maria O'Donovan, Richard Newton, Lorenz Wernisch, Nicholas B. Shannon, Kareem Shariff, Massimiliano di Pietro, Jacques J.G.H.M. Bergman, Krish Ragunath, Rebecca C. Fitzgerald

Abstract

Endoscopic surveillance of Barrett's esophagus is problematic because dysplasia/early-stage neoplasia is frequently invisible and likely to be missed because of sampling bias. Molecular abnormalities may be more diffuse than dysplasia. The aim was therefore to test whether DNA methylation, especially on imprinted and X-chromosome genes, is able to detect dysplasia/early-stage neoplasia.

X Demographics

X Demographics

The data shown below were collected from the profiles of 2 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 70 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 1%
Unknown 69 99%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 16 23%
Researcher 16 23%
Professor 6 9%
Student > Doctoral Student 5 7%
Other 5 7%
Other 15 21%
Unknown 7 10%
Readers by discipline Count As %
Medicine and Dentistry 31 44%
Agricultural and Biological Sciences 11 16%
Biochemistry, Genetics and Molecular Biology 6 9%
Nursing and Health Professions 4 6%
Immunology and Microbiology 2 3%
Other 7 10%
Unknown 9 13%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 11. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 June 2021.
All research outputs
#2,859,805
of 22,689,790 outputs
Outputs from Clinical Cancer Research
#2,495
of 12,572 outputs
Outputs of similar age
#32,029
of 287,561 outputs
Outputs of similar age from Clinical Cancer Research
#24
of 169 outputs
Altmetric has tracked 22,689,790 research outputs across all sources so far. Compared to these this one has done well and is in the 87th percentile: it's in the top 25% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 12,572 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 10.7. This one has done well, scoring higher than 79% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 287,561 tracked outputs that were published within six weeks on either side of this one in any source. This one has done well, scoring higher than 88% of its contemporaries.
We're also able to compare this research output to 169 others from the same source and published within six weeks on either side of this one. This one has done well, scoring higher than 85% of its contemporaries.