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Rotavirus acceleration of murine type 1 diabetes is associated with a T helper 1-dependent specific serum antibody response and virus effects in regional lymph nodes

Overview of attention for article published in Diabetologia, December 2012
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Title
Rotavirus acceleration of murine type 1 diabetes is associated with a T helper 1-dependent specific serum antibody response and virus effects in regional lymph nodes
Published in
Diabetologia, December 2012
DOI 10.1007/s00125-012-2798-4
Pubmed ID
Authors

J. A. Pane, N. L. Webster, K. L. Graham, G. Holloway, C. Zufferey, B. S. Coulson

Abstract

Rotavirus infection in at-risk children correlates with production of serum autoantibodies indicative of type 1 diabetes progression. Oral infection with rhesus monkey rotavirus (RRV) accelerates diabetes onset in mice. This relates to their rotavirus-specific serum antibody titre and local pro-inflammatory cytokine induction without pancreatic infection. Our aim was to further investigate the roles of serum antibodies and viral extra-intestinal spread in diabetes acceleration by rotavirus.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 20 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 20 100%

Demographic breakdown

Readers by professional status Count As %
Professor > Associate Professor 4 20%
Student > Ph. D. Student 3 15%
Researcher 3 15%
Other 2 10%
Student > Bachelor 1 5%
Other 2 10%
Unknown 5 25%
Readers by discipline Count As %
Medicine and Dentistry 6 30%
Agricultural and Biological Sciences 4 20%
Immunology and Microbiology 3 15%
Pharmacology, Toxicology and Pharmaceutical Science 1 5%
Engineering 1 5%
Other 0 0%
Unknown 5 25%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 15 December 2012.
All research outputs
#18,323,689
of 22,689,790 outputs
Outputs from Diabetologia
#4,666
of 5,025 outputs
Outputs of similar age
#216,522
of 278,890 outputs
Outputs of similar age from Diabetologia
#27
of 41 outputs
Altmetric has tracked 22,689,790 research outputs across all sources so far. This one is in the 11th percentile – i.e., 11% of other outputs scored the same or lower than it.
So far Altmetric has tracked 5,025 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 22.6. This one is in the 3rd percentile – i.e., 3% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 278,890 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 11th percentile – i.e., 11% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 41 others from the same source and published within six weeks on either side of this one. This one is in the 2nd percentile – i.e., 2% of its contemporaries scored the same or lower than it.