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X Demographics
Mendeley readers
Attention Score in Context
| Title |
Local Anesthetic–Induced Inhibition of Human Neutrophil Priming
|
|---|---|
| Published in |
Regional Anesthesia & Pain Medicine, January 2013
|
| DOI | 10.1097/aap.0b013e31827a3cbe |
| Pubmed ID | |
| Authors |
Susanne Picardi, Sibylle Cartellieri, Danja Groves, Klaus Hahnenekamp, Peter Gerner, Marcel E. Durieux, Markus F. Stevens, Philipp Lirk, Markus W. Hollmann |
| Abstract |
Local anesthetics (LAs) are widely known for inhibition of voltage-gated sodium channels underlying their antiarrhythmic and antinociceptive effects. However, LAs have significant immunomodulatory properties and were shown to affect human neutrophil functions independent of sodium-channel blockade. Previous studies suggest a highly selective interaction between LAs and the α-subunit of G protein-coupled receptors of the Gq/G11 family as underlying mechanism. Providing a detailed structure function analysis, this study aimed to determine the active parts within the LA molecule responsible for the effects on human neutrophil priming. |
X Demographics
The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| United States | 1 | 100% |
Demographic breakdown
| Type | Count | As % |
|---|---|---|
| Practitioners (doctors, other healthcare professionals) | 1 | 100% |
Mendeley readers
The data shown below were compiled from readership statistics for 17 Mendeley readers of this research output. Click here to see the associated Mendeley record.
Geographical breakdown
| Country | Count | As % |
|---|---|---|
| Unknown | 17 | 100% |
Demographic breakdown
| Readers by professional status | Count | As % |
|---|---|---|
| Other | 3 | 18% |
| Student > Postgraduate | 3 | 18% |
| Lecturer > Senior Lecturer | 2 | 12% |
| Professor | 2 | 12% |
| Student > Ph. D. Student | 1 | 6% |
| Other | 3 | 18% |
| Unknown | 3 | 18% |
| Readers by discipline | Count | As % |
|---|---|---|
| Medicine and Dentistry | 11 | 65% |
| Agricultural and Biological Sciences | 1 | 6% |
| Chemistry | 1 | 6% |
| Neuroscience | 1 | 6% |
| Unknown | 3 | 18% |
Attention Score in Context
This research output has an Altmetric Attention Score of 2. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 03 October 2016.
All research outputs
#15,739,529
of 25,373,627 outputs
Outputs from Regional Anesthesia & Pain Medicine
#1,685
of 2,571 outputs
Outputs of similar age
#177,354
of 288,991 outputs
Outputs of similar age from Regional Anesthesia & Pain Medicine
#50
of 138 outputs
Altmetric has tracked 25,373,627 research outputs across all sources so far. This one is in the 37th percentile – i.e., 37% of other outputs scored the same or lower than it.
So far Altmetric has tracked 2,571 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 9.8. This one is in the 32nd percentile – i.e., 32% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 288,991 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 37th percentile – i.e., 37% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 138 others from the same source and published within six weeks on either side of this one. This one has gotten more attention than average, scoring higher than 60% of its contemporaries.