Effect of Maintenance Tocolysis With Nifedipine in Threatened Preterm Labor on Perinatal Outcomes: A Randomized Controlled Trial

Overview of attention for article published in JAMA: Journal of the American Medical Association, January 2013

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Maintenance tocolysis with nifedipine is useless http://t.co/jxuRfi3A

結果：妊娠期間は両群とも29.2週。有害周産期アウトカムはニフェジピン群で24/201 11.9%(7.5-16.4)、プラセボ群で28/205 13.7%(9.0-18.4)、RR=0.87(0.53-1.45)。有意差はなかった。 http://t.co/NFhFbejd

P:妊娠周期26週～32週の切迫早産女性 E:経口ニフェジピン80mg/dayを12日間投与 C:プラセボ12日間投与 O:有害周産期アウトカム（周産期死亡・新生児敗血症など） RCT、多施設、ITT解析 http://t.co/NFhFbejd

Ca拮抗薬は子宮筋の収縮を抑制するため切迫早産に使用されることもあるそう。はたしてその効果は？ http://t.co/NFhFbejd

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