Title |
Altered BANK1 expression is not associated with humoral autoimmunity in chronic joint inflammation
|
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Published in |
Rheumatology, October 2012
|
DOI | 10.1093/rheumatology/kes247 |
Pubmed ID | |
Authors |
Tineke Cantaert, Natalyia G. Yeremenko, Christine A. Teitsma, Leonie M. van Duivenvoorde, Jackeline E. Paramarta, Paul-Peter Tak, Dominique L. Baeten |
Abstract |
The presence of disease-specific autoantibodies in RA but not spondyloarthritis (SpA) suggests that B-cell tolerance is preserved in the latter condition despite chronic joint inflammation. Which factors control B-cell tolerance vs autoimmunity in chronic arthritis remains incompletely understood. As single nucleotide polymorphisms in the B-cell scaffold protein with ankyrin repeats (BANK1) gene have recently been associated with various autoantibody-positive autoimmune diseases including RA, we explored whether altered expression of BANK1 was associated with humoral autoimmunity in arthritis. |
X Demographics
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United States | 1 | 100% |
Demographic breakdown
Type | Count | As % |
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Members of the public | 1 | 100% |
Mendeley readers
Geographical breakdown
Country | Count | As % |
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United Kingdom | 1 | 5% |
Unknown | 18 | 95% |
Demographic breakdown
Readers by professional status | Count | As % |
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Student > Master | 6 | 32% |
Other | 2 | 11% |
Researcher | 2 | 11% |
Student > Ph. D. Student | 2 | 11% |
Student > Bachelor | 1 | 5% |
Other | 1 | 5% |
Unknown | 5 | 26% |
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Medicine and Dentistry | 4 | 21% |
Agricultural and Biological Sciences | 2 | 11% |
Psychology | 2 | 11% |
Immunology and Microbiology | 2 | 11% |
Biochemistry, Genetics and Molecular Biology | 1 | 5% |
Other | 2 | 11% |
Unknown | 6 | 32% |