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What Drives the Number of High-Risk Human Papillomavirus Types in the Anal Canal in HIV-Positive Men Who Have Sex With Men?

Overview of attention for article published in Journal of Infectious Diseases, January 2013
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52 Mendeley
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Title
What Drives the Number of High-Risk Human Papillomavirus Types in the Anal Canal in HIV-Positive Men Who Have Sex With Men?
Published in
Journal of Infectious Diseases, January 2013
DOI 10.1093/infdis/jit028
Pubmed ID
Authors

J. Del Amo, C. Gonzalez, R. B. Geskus, M. Torres, J. Del Romero, P. Viciana, M. Masia, J. R. Blanco, B. Hernandez-Novoa, M. Ortiz,, A. Pena, F. Garcia;, M. Ortiz, M. Torres, A. Ocampo, A. R. Da Silva, C. Miralles, G. Mauricio Iribarren, B. Hernandez-Novoa, N. Madrid, F. Dronda, A. Benito, I. Sanz, J. del Romero, M. Vera, C. Rodriguez, C. Martin Alegre, J. Carlos Carrio, M. Raposo, P. Viciana, M. Trastoy, M. Fontillon, M. Masia, C. Robledano, F. Gutierrez, S. Padilla, E. Andrada, M. Cervero, J. Ramon Blanco, L. Perez, J. Portilla, I. Portilla, M. Angel Vonwichmann, J. Antonio Iribarren, X. Camino, E. Sendagorta, P. Herranz, P. Rodriguez, J. Luis Gomez, D. Rosado, J. del Amo, C. Gonzalez, B. Alejos, M. Angeles Rodriguez

Abstract

We estimated the effect of sexual behavior, age, and immunodeficiency on the number of high-risk human papillomavirus (HR-HPV) types in the anal canal among human immunodeficiency virus-positive men who have sex with men (MSM). Anal samples were genotyped with the Linear Array HPV Genotyping Test, and risk factors were investigated with Poisson regression. Of 586 MSM, 69% were Spanish, and 25.6% were Latin American; the median age was 34.9 years (interquartile range [IQR], 30.1-40.8). The median number of recent sex partners was 6 (IQR, 2-24 sex partners), and the median CD4(+) T-cell count was 531.5 cells/mm(3) (IQR, 403-701 cells/mm(3)). The prevalence of any and multiple HR-HPV infections was 83.4% and 60.5%, respectively. The most common types were HPV-16 (42%), HPV-51 (24%), HPV-39 (23.7%), and HPV-59 (23.5%). Age had a statistically significant, nonlinear association with the number of types, with the highest number detected around 35 years of age (P < .001). The number of recent sex partners had a statistically significant, fairly linear association on the log scale (P = .033). The high prevalence of HR-HPV types is associated with recent sexual behavior and age.

X Demographics

X Demographics

The data shown below were collected from the profiles of 4 X users who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 52 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United States 1 2%
Unknown 51 98%

Demographic breakdown

Readers by professional status Count As %
Researcher 12 23%
Student > Master 6 12%
Student > Ph. D. Student 5 10%
Professor > Associate Professor 5 10%
Student > Bachelor 4 8%
Other 12 23%
Unknown 8 15%
Readers by discipline Count As %
Medicine and Dentistry 18 35%
Nursing and Health Professions 4 8%
Immunology and Microbiology 4 8%
Social Sciences 4 8%
Agricultural and Biological Sciences 2 4%
Other 9 17%
Unknown 11 21%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 3. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 09 February 2013.
All research outputs
#14,278,028
of 25,374,647 outputs
Outputs from Journal of Infectious Diseases
#11,404
of 14,795 outputs
Outputs of similar age
#165,067
of 292,951 outputs
Outputs of similar age from Journal of Infectious Diseases
#72
of 110 outputs
Altmetric has tracked 25,374,647 research outputs across all sources so far. This one is in the 43rd percentile – i.e., 43% of other outputs scored the same or lower than it.
So far Altmetric has tracked 14,795 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 16.4. This one is in the 22nd percentile – i.e., 22% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 292,951 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 43rd percentile – i.e., 43% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 110 others from the same source and published within six weeks on either side of this one. This one is in the 32nd percentile – i.e., 32% of its contemporaries scored the same or lower than it.