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Acute Central Neuropeptide Y Administration Increases Food Intake but Does Not Affect Hepatic Very Low-Density Lipoprotein (Vldl) Production in Mice

Overview of attention for article published in PLOS ONE, February 2013
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Title
Acute Central Neuropeptide Y Administration Increases Food Intake but Does Not Affect Hepatic Very Low-Density Lipoprotein (Vldl) Production in Mice
Published in
PLOS ONE, February 2013
DOI 10.1371/journal.pone.0055217
Pubmed ID
Authors

Janine J. Geerling, Yanan Wang, Louis M. Havekes, Johannes A. Romijn, Patrick C. N. Rensen

Abstract

Central neuropeptide Y (NPY) administration stimulates food intake in rodents. In addition, acute modulation of central NPY signaling increases hepatic production of very low-density lipoprotein (VLDL)-triglyceride (TG) in rats. As hypertriglyceridemia is an important risk factor for atherosclerosis, for which well-established mouse models are available, we set out to validate the effect of NPY on hepatic VLDL-TG production in mice, to ultimately investigate whether NPY, by increasing VLDL production, contributes to the development of atherosclerosis.

Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 19 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Netherlands 1 5%
Unknown 18 95%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 8 42%
Student > Master 3 16%
Professor > Associate Professor 3 16%
Researcher 2 11%
Student > Postgraduate 1 5%
Other 0 0%
Unknown 2 11%
Readers by discipline Count As %
Agricultural and Biological Sciences 7 37%
Medicine and Dentistry 5 26%
Neuroscience 3 16%
Sports and Recreations 1 5%
Engineering 1 5%
Other 0 0%
Unknown 2 11%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 28 February 2013.
All research outputs
#20,184,694
of 22,699,621 outputs
Outputs from PLOS ONE
#172,949
of 193,796 outputs
Outputs of similar age
#169,542
of 192,966 outputs
Outputs of similar age from PLOS ONE
#4,396
of 5,355 outputs
Altmetric has tracked 22,699,621 research outputs across all sources so far. This one is in the 1st percentile – i.e., 1% of other outputs scored the same or lower than it.
So far Altmetric has tracked 193,796 research outputs from this source. They typically receive a lot more attention than average, with a mean Attention Score of 15.0. This one is in the 1st percentile – i.e., 1% of its peers scored the same or lower than it.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 192,966 tracked outputs that were published within six weeks on either side of this one in any source. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.
We're also able to compare this research output to 5,355 others from the same source and published within six weeks on either side of this one. This one is in the 1st percentile – i.e., 1% of its contemporaries scored the same or lower than it.