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Clinical predictors of seizure recurrence after the first post-ischemic stroke seizure

Overview of attention for article published in BMC Neurology, November 2016
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Title
Clinical predictors of seizure recurrence after the first post-ischemic stroke seizure
Published in
BMC Neurology, November 2016
DOI 10.1186/s12883-016-0729-6
Pubmed ID
Authors

Hyeon Jin Kim, Kee Duk Park, Kyoung-Gyu Choi, Hyang Woon Lee

Abstract

The number of patients suffering post-stroke seizure after ischemic stroke (PSSi) is quite considerable, especially because ischemic stroke is more prevalent than hemorrhage in the general population. This study aimed to determine the predicting factors for seizure recurrence in ischemic stroke survivors and develop a clinical scoring system for the prediction of risks for seizure recurrence after the first PSSi. We reviewed 3792 ischemic stroke patients from the Ewha Stroke Registry. A total of 124 (3.3 %) patients who experienced PSSi were recruited (mean follow-up for 44.4 months). Medical records concerning the etiology, functional disability, seizure onset latency from stroke, type of seizure, electroencephalography (EEG), and neuroimaging findings were statistically analyzed to derive a seizure recurrence risk scoring system. Seizures recurred in 35.4 % (17/48) of early PSSi patients (≤1 week since stroke onset) and 48.7 % (37/76) of late PSSi (>1 week) patients. Atrial fibrillation, large sized, and cortical stroke lesion were more common in late onset PSSi compared to those in early onset PSSi (p < 0.05). Seizure recurrence tended to be more prevalent in early PSSi patients with male gender, atrial fibrillation or cortical stroke lesion, severe functional disability, and partial seizures. Seizure recurrence in late PSSi group was more common in patients of young age (≤65 years old), male gender, large lesion size, and partial seizure type. The validity of seizure recurrence risk score in the early PSSi group was better when evaluating based on gender, atrial fibrillation, cortical lesion, functional disability, and partial seizure type, with sensitivity of 70.6 % and specificity of 71.0 %. Our study characterized the high risk group for seizure recurrence in patients with the first PSSi. PSSi patients with high risk score of seizure recurrence had a greater chance of developing epilepsy later. Therefore, they should be considered for further treatment such as antiepileptic drug medication in clinical practice.

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 119 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
United Kingdom 1 <1%
Unknown 118 99%

Demographic breakdown

Readers by professional status Count As %
Other 17 14%
Student > Bachelor 13 11%
Researcher 12 10%
Student > Postgraduate 12 10%
Student > Master 10 8%
Other 28 24%
Unknown 27 23%
Readers by discipline Count As %
Medicine and Dentistry 54 45%
Neuroscience 16 13%
Nursing and Health Professions 4 3%
Agricultural and Biological Sciences 3 3%
Psychology 3 3%
Other 5 4%
Unknown 34 29%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 1. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 05 May 2017.
All research outputs
#18,937,691
of 24,135,931 outputs
Outputs from BMC Neurology
#1,902
of 2,565 outputs
Outputs of similar age
#227,158
of 315,964 outputs
Outputs of similar age from BMC Neurology
#37
of 49 outputs
Altmetric has tracked 24,135,931 research outputs across all sources so far. This one is in the 18th percentile – i.e., 18% of other outputs scored the same or lower than it.
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