↓ Skip to main content

Norepinephrine: A Neuromodulator That Boosts the Function of Multiple Cell Types to Optimize CNS Performance

Overview of attention for article published in Neurochemical Research, June 2012
Altmetric Badge

About this Attention Score

  • In the top 25% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#44 of 2,172)
  • High Attention Score compared to outputs of the same age (92nd percentile)
  • High Attention Score compared to outputs of the same age and source (96th percentile)

Mentioned by

news
1 news outlet
twitter
1 X user
patent
1 patent
wikipedia
2 Wikipedia pages
video
2 YouTube creators

Citations

dimensions_citation
261 Dimensions

Readers on

mendeley
384 Mendeley
citeulike
2 CiteULike
You are seeing a free-to-access but limited selection of the activity Altmetric has collected about this research output. Click here to find out more.
Title
Norepinephrine: A Neuromodulator That Boosts the Function of Multiple Cell Types to Optimize CNS Performance
Published in
Neurochemical Research, June 2012
DOI 10.1007/s11064-012-0818-x
Pubmed ID
Authors

John O’Donnell, Douglas Zeppenfeld, Evan McConnell, Salvador Pena, Maiken Nedergaard

Abstract

Norepinephrine (NE) is a neuromodulator that in multiple ways regulates the activity of neuronal and non-neuronal cells. NE participates in the rapid modulation of cortical circuits and cellular energy metabolism, and on a slower time scale in neuroplasticity and inflammation. Of the multiple sources of NE in the brain, the locus coeruleus (LC) plays a major role in noradrenergic signaling. Processes from the LC primarily release NE over widespread brain regions via non-junctional varicosities. We here review the actions of NE in astrocytes, microglial cells, and neurons based on the idea that the overarching effect of signaling from the LC is to maximize brain power, which is accomplished via an orchestrated cellular response involving most, if not all cell types in CNS.

X Demographics

X Demographics

The data shown below were collected from the profile of 1 X user who shared this research output. Click here to find out more about how the information was compiled.
Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 384 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Japan 3 <1%
United States 3 <1%
Mexico 1 <1%
France 1 <1%
Unknown 376 98%

Demographic breakdown

Readers by professional status Count As %
Student > Ph. D. Student 67 17%
Student > Bachelor 60 16%
Student > Master 50 13%
Researcher 45 12%
Other 14 4%
Other 65 17%
Unknown 83 22%
Readers by discipline Count As %
Neuroscience 108 28%
Agricultural and Biological Sciences 58 15%
Medicine and Dentistry 36 9%
Biochemistry, Genetics and Molecular Biology 33 9%
Psychology 11 3%
Other 39 10%
Unknown 99 26%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 16. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 21 December 2023.
All research outputs
#2,027,066
of 23,896,578 outputs
Outputs from Neurochemical Research
#44
of 2,172 outputs
Outputs of similar age
#12,508
of 166,091 outputs
Outputs of similar age from Neurochemical Research
#2
of 28 outputs
Altmetric has tracked 23,896,578 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 91st percentile: it's in the top 10% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 2,172 research outputs from this source. They receive a mean Attention Score of 4.5. This one has done particularly well, scoring higher than 98% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 166,091 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 92% of its contemporaries.
We're also able to compare this research output to 28 others from the same source and published within six weeks on either side of this one. This one has done particularly well, scoring higher than 96% of its contemporaries.