Alterations in the neuropeptide galanin system in major depressive disorder involve levels of transcripts, methylation, and peptide

Overview of attention for article published in Proceedings of the National Academy of Sciences of the United States of America, December 2016

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自殺したうつ病の人の死後脳で青斑核、背側縫線核でガラニンやその受容体の1つであるGALR3に関するmRNA発現が亢進。これは男女共通だが、外外側前頭前野でのガラニン/GALR3転写レベルの低下、GALR1、メチル化の亢進は男性だけ。https://t.co/cmtAyjTUuI

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