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Antioxidant effects of curcuminoids in patients with type 2 diabetes mellitus: a randomized controlled trial

Overview of attention for article published in Inflammopharmacology, December 2016
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About this Attention Score

  • In the top 5% of all research outputs scored by Altmetric
  • Among the highest-scoring outputs from this source (#25 of 539)
  • High Attention Score compared to outputs of the same age (94th percentile)
  • Good Attention Score compared to outputs of the same age and source (66th percentile)

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3 news outlets
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1 blog
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3 Facebook pages

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185 Mendeley
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Title
Antioxidant effects of curcuminoids in patients with type 2 diabetes mellitus: a randomized controlled trial
Published in
Inflammopharmacology, December 2016
DOI 10.1007/s10787-016-0301-4
Pubmed ID
Authors

Yunes Panahi, Nahid Khalili, Ebrahim Sahebi, Soha Namazi, Maryam Saberi Karimian, Muhammed Majeed, Amirhossein Sahebkar

Abstract

Oxidative stress has a key role in the pathogenesis of type II diabetes mellitus (T2DM) and its vascular complications. Antioxidant therapy has been suggested as a potential approach to blunt T2DM development and progression. The aim of this study was to assess the effects of supplementation with curcuminoids, which are natural polyphenolics from turmeric, on oxidative indices in diabetic individuals. In this randomized double-blind placebo-controlled trial, 118 subjects with T2DM were randomized to curcuminoids (1000 mg/day co-administered with piperine 10 mg/day) or matching placebo for a period of 8 weeks. Serum total antioxidant capacity, superoxide dismutase (SOD) activities and malondialdehyde (MDA) concentrations were measured at baseline and after the supplementation period. Curcuminoids supplementation caused a significant elevation in serum total antioxidant capacity (TAC) (p < 0.001) and SOD activities (p < 0.001), while serum MDA levels were significantly reduced compared with the placebo group (p < 0.001). These results remained statistically significant after adjustment for potential confounders (baseline differences in body mass index and fasting serum insulin). The present results support an antioxidant effect of curcuminoids supplementation in patients with T2DM, and call for future studies to assess the impact of these antioxidant effects on the occurrence of diabetic complications and cardiovascular endpoints.

X Demographics

X Demographics

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Mendeley readers

Mendeley readers

The data shown below were compiled from readership statistics for 185 Mendeley readers of this research output. Click here to see the associated Mendeley record.

Geographical breakdown

Country Count As %
Unknown 185 100%

Demographic breakdown

Readers by professional status Count As %
Student > Master 28 15%
Student > Bachelor 28 15%
Researcher 19 10%
Student > Ph. D. Student 15 8%
Other 4 2%
Other 19 10%
Unknown 72 39%
Readers by discipline Count As %
Medicine and Dentistry 26 14%
Nursing and Health Professions 18 10%
Biochemistry, Genetics and Molecular Biology 18 10%
Pharmacology, Toxicology and Pharmaceutical Science 14 8%
Agricultural and Biological Sciences 10 5%
Other 22 12%
Unknown 77 42%
Attention Score in Context

Attention Score in Context

This research output has an Altmetric Attention Score of 35. This is our high-level measure of the quality and quantity of online attention that it has received. This Attention Score, as well as the ranking and number of research outputs shown below, was calculated when the research output was last mentioned on 30 October 2018.
All research outputs
#983,219
of 22,912,409 outputs
Outputs from Inflammopharmacology
#25
of 539 outputs
Outputs of similar age
#22,193
of 419,650 outputs
Outputs of similar age from Inflammopharmacology
#2
of 6 outputs
Altmetric has tracked 22,912,409 research outputs across all sources so far. Compared to these this one has done particularly well and is in the 95th percentile: it's in the top 5% of all research outputs ever tracked by Altmetric.
So far Altmetric has tracked 539 research outputs from this source. They typically receive more attention than average, with a mean Attention Score of 8.5. This one has done particularly well, scoring higher than 95% of its peers.
Older research outputs will score higher simply because they've had more time to accumulate mentions. To account for age we can compare this Altmetric Attention Score to the 419,650 tracked outputs that were published within six weeks on either side of this one in any source. This one has done particularly well, scoring higher than 94% of its contemporaries.
We're also able to compare this research output to 6 others from the same source and published within six weeks on either side of this one. This one has scored higher than 4 of them.